PHR1621

硝酸布康唑

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: Butoconazole nitrate, (±)-1-[4-(4-Chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole mononitrate
• 经验公式（希尔记法）: C₁₉H₁₇Cl₃N₂S · HNO₃
• CAS号: 64872-77-1
• 分子量: 474.79
• MDL编号: MFCD00058159
• UNSPSC代码: 41116107
• PubChem化学物质编号: 329823515
• NACRES: NA.24

属性

• 等级: certified reference material; pharmaceutical secondary standard
• 质量水平: 300
• Agency: traceable to USP 1082300
• API类: butoconazole
• CofA: current certificate can be downloaded
• 包装: pkg of 1 g
• 技术: HPLC: suitable; gas chromatography (GC): suitable
• 应用: pharmaceutical (small molecule)
• 包装形式: neat
• 储存温度: 2-30°C
• SMILES字符串: ClC1=C(C(Cl)=CC=C1)SC(CCC2=CC=C(Cl)C=C2)CN3C=CN=C3.O[N+]([O-])=O
• InChI: 1S/C19H17Cl3N2S.HNO3/c20-15-7-4-14(5-8-15)6-9-16(12-24-11-10-23-13-24)25-19-17(21)2-1-3-18(19)22;2-1(3)4/h1-5,7-8,10-11,13,16H,6,9,12H2;(H,2,3,4)
• InChI key: ZHPWRQIPPNZNML-UHFFFAOYSA-N

说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Butoconazole nitrate is an antifungal agent belonging to the imidazole class, used for the treatment of vaginal candidiasis. Its mode of action includes interruption of synthesis of cellular ergosterol and disruption of cell membrane.[1]

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA5291 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全信息

• 象形图: GHS07
• 警示用语：: Warning
• 危险声明: H302
• 危险分类: Acute Tox. 4 Oral
• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable