PHR1587

硫柳汞钠

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: 硫柳汞钠, Mercury-([o-carboxyphenyl]thio)ethyl 钠盐, 乙基噻吩酸 钠盐, 乙汞硫柳酸钠, 乙汞硫水杨酸 钠盐
• 线性分子式: 2-(C₂H₅HgS)C₆H₄CO₂Na
• CAS号: 54-64-8
• 分子量: 404.81
• Beilstein: 8169555
• EC 号: 200-210-4
• MDL编号: MFCD00013062
• UNSPSC代码: 41116107
• PubChem化学物质编号: 329823493
• NACRES: NA.24

属性

• 等级: certified reference material; pharmaceutical secondary standard
• 质量水平: 300
• Agency: traceable to Ph. Eur. Y0000109; traceable to USP 1659000
• API类: thimerosal
• CofA: current certificate can be downloaded
• 包装: pkg of 1 g
• 技术: HPLC: suitable; gas chromatography (GC): suitable
• mp: 234-237 °C (dec.) (lit.)
• 应用: pharmaceutical (small molecule)
• 包装形式: neat
• 储存温度: 2-30°C
• SMILES字符串: [Na+].CC[Hg]Sc1ccccc1C([O-])=O
• InChI: 1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
• InChI key: RTKIYNMVFMVABJ-UHFFFAOYSA-L

说明

一般描述

Thimerosal belongs to the group of alkyl mercury compounds. Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Thimerosal may be used as a pharmaceutical reference standard for the quantification of the analyte in ophthalmic solutions using spectrophotometric technique.[1]

生化/生理作用

硫柳汞是一种巯基（硫醇）氧化剂，能抑制多种巯基依赖性酶和蛋白质，如PI3激酶依赖性蛋氨酸合成酶、谷氨酸转运受体和Na⁺+K⁺依赖性ATP酶。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA6959 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

免责声明

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

安全信息

• 象形图: GHS06,GHS08,GHS09
• 警示用语：: Danger
• 危险声明: H300 + H310 + H330,H373,H410
• 预防措施声明: P262 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• 危险分类: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral
• 靶器官: Kidney
• 储存分类代码: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable