PHR1353

雌二醇

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: β-雌二醇, 17β-雌二醇, 1，3，5-雌三烯-3，17β-二醇, 3,17β-二羟基-1,3,5(10)-雌三烯, 二氢卵泡素
• 经验公式（希尔记法）: C₁₈H₂₄O₂
• CAS号: 50-28-2
• 分子量: 272.38
• Beilstein: 1914275
• EC號碼: 200-023-8
• MDL號碼: MFCD00003693
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823337
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to BP 729; traceable to Ph. Eur. E1620000; traceable to USP 1250008
• API 家族: estradiol
• CofA: current certificate can be downloaded
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• mp: 176-180 °C (lit.)
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: 2-30°C
• SMILES 字串: O[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(O)=CC=C4[C@@]3([H])CC[C@@]21C
• InChI: 1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
• InChI 密鑰: VOXZDWNPVJITMN-ZBRFXRBCSA-N
• 基因資訊: human ... ESR1(2099)

说明

一般說明

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Estradiol is a steroid hormone present naturally in the human body. The availability of this hormone is quintessential in older women as it is a determinant of menopausal syndromes. It is utilized for the prevention of cardiovascular diseases.

應用

Estradiol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

绝经前卵巢分泌的主要雌激素。雌激素通过调节基因转录并因此调节蛋白质合成来指导胚胎发生和青春期女性表型的发展。 它还诱导促性腺激素的产生，进而诱导排卵。 暴露于雌二醇会增加乳腺癌的发生率和增殖。

分析報告

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAC3704 in the slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全信息

• 象形圖: GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H351,H360FD,H362,H410
• 防範說明: P202 - P260 - P263 - P264 - P273 - P308 + P313
• 危險分類: Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 1A
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable