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Merck

PHR1343

Supelco

磺胺嘧啶

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

磺胺嘧啶, N-2-嘧啶基-4-氨基苯磺酰胺, N1-(嘧啶-2-基)磺胺

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About This Item

经验公式(希尔记法):
C10H10N4O2S
CAS号:
分子量:
250.28
Beilstein:
6733588
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to Ph. Eur. S1800000
traceable to USP 1625009

API 家族

sulfadiazine

CofA

current certificate can be downloaded

技術

HPLC: suitable
gas chromatography (GC): suitable

mp

253 °C (dec.) (lit.)

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-30°C

SMILES 字串

Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2

InChI

1S/C10H10N4O2S/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10/h1-7H,11H2,(H,12,13,14)

InChI 密鑰

SEEPANYCNGTZFQ-UHFFFAOYSA-N

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一般說明

Sulfadiazine is a bacteriostatic drug, that belongs to the class of medication referred as sulfonamide antibiotics. It is generally used in the treatment of cerebral meningitis, pneumonia, staphylococcal and streptococcal sepsis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Sulfadiazine may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAC3953 in the slot below. This is an example certificate only and may not be the lot that you receive.

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2


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分析证书(COA)

Lot/Batch Number

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访问文档库

Development and validation of a stability-indicating HPLC method for the simultaneous determination of sulfadiazine sodium and trimethoprim in injectable solution formulation
Ghanem MM and Abu-Lafi SA
Scientia Pharmaceutica, 81(1), 167-182 (2013)
Sulfadiazine
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3674-3675 (2017)
Simultaneous determination of enrofloxacin, silver sulfadiazine, hydrocortisone acetate, hydrocortisone sodium succinate, and preservative excipients in pharmaceutical preparations using HPLC-DAD method
Rosa AM, et al.
Chromatographia, 80(11), 1641-1649 (2017)
Determination of the content and the related substances of silver sulfadiazine gel by HPLC
Li Y, et al.
Chinese Journal of Hospital Pharmacy, 24(8), 474-474 (2004)
33 - Antimicrobial Drugs
Synthesis of Essential Drugs, 499-523 (2006)

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