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Merck
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文件

D9900

Supelco

地西泮标准液 溶液

1.0 mg/mL in methanol, analytical standard, for drug analysis

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About This Item

经验公式（希尔记法）:
C16H13ClN2O
CAS号:
439-14-5
分子量:
284.74
EC號碼:
200-659-6
MDL號碼:
MFCD00057323
分類程式碼代碼:
41116107
PubChem物質ID:
329798914
NACRES:
NA.24

等級

analytical standard, for drug analysis

品質等級

200

drug control

Home Office Schedule 4.1; psychotrope (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

濃度

1.0 mg/mL in methanol

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)

格式

single component solution

儲存溫度

2-8°C

SMILES 字串

CN1C(=O)CN=C(c2ccccc2)c3cc(Cl)ccc13

InChI

1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3

InChI 密鑰

AAOVKJBEBIDNHE-UHFFFAOYSA-N

基因資訊

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)
mouse ... Gabrg2(14406)
rat ... Gabra1(29705) , Gabra2(29706)

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應用

有关合适的仪器技术的更多信息，请参阅产品′检验报告。想要获得更多支持，请联系技术服务部。

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

51.8 °F - closed cup

閃點（°C）

11 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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分析证书(COA)

Lot/Batch Number
SLCJ4445
SLCD5357
SLBV6203
SLBN3040V
SLBC0394V

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氯化锂 for molecular biology, ≥99%

Sigma-Aldrich

L9650

氯化锂

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The 3-ethoxycarbonyl-4-quinolone compound 1 has previously been identified via a database search as an interesting lead compound for ligand binding at the benzodiazepine site of GABA(A) receptors (Kahnberg et al. J. Mol. Graphics Modelling 2004, 23, 253-261). Pharmacophore-guided optimization of
Barbara Taferner et al.
Journal of medicinal chemistry, 54(15), 5349-5361 (2011-06-28)
A series of 31 analogues of the neolignan honokiol (a major constituent of Magnolia officinalis) was synthesized, and their effects on GABA(A) receptors expressed in Xenopus oocytes were investigated. Honokiol enhanced chloride currents (I(GABA)) through GABA(A) receptors of seven different
Shoukou Lee et al.
Bioorganic & medicinal chemistry, 16(21), 9519-9523 (2008-10-03)
The pyrimido[1,2-a][1,4]benzodiazepines (1a-c) and the 8-membered analogues (diazocines 2a and 2b) were separated into their atropisomers with HPLC on a chiral column. High stereochemical stability was observed in the atropisomer of the 8-membered derivatives (2a and 2b), and the 1,4-benzodiazepine
Elisabet Lázaro et al.
Journal of medicinal chemistry, 51(7), 2009-2017 (2008-03-20)
We report here a new, label-free approach to measure serum protein binding constants. The assay is able to measure HSA K d values in the milli-molar to micromolar range. The protein is not immobilized on any surface and the assay
The translocator protein (18 kDa): central nervous system disease and drug design.
Alana M Scarf et al.
Journal of medicinal chemistry, 52(3), 581-592 (2009-01-13)
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