D2975000

阿霉素 盐酸盐

European Pharmacopoeia (EP) Reference Standard

• 别名: DOX, 多柔比星^® 盐酸盐, 羟基柔红霉素 盐酸盐
• 经验公式（希尔记法）: C₂₇H₂₉NO₁₁ · HCl
• CAS号: 25316-40-9
• 分子量: 579.98
• Beilstein: 4229251
• EC 号: 246-818-3
• MDL编号: MFCD00077757
• UNSPSC代码: 41116107
• PubChem化学物质编号: 329798767
• NACRES: NA.24

属性

• 等级: pharmaceutical primary standard
• API类: doxorubicin
• 制造商/商品名称: EDQM
• mp: 216 °C (dec.) (lit.)
• 应用: pharmaceutical (small molecule)
• 包装形式: neat
• SMILES字符串: Cl[H].COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
• InChI: 1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
• InChI key: MWWSFMDVAYGXBV-RUELKSSGSA-N
• 基因信息: human ... TOP2A(7153)

说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the Issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Produced by certain strains of Streptomyces coeruleorubidus or Streptomyces peucetius or obtained by any other means.

应用

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia. Their suitability for any other use is not guaranteed and is the sole responsibility of the user. This standard is not intended for human or animal use.
Established for the preparation of the below-given solutions as per European Pharmacopoeia:

• Reference solutions (b) and (c) in the testing of related substances in daunorubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 0662
• Reference solutions (a) and (c) to test related substances in doxorubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 0714
• Reference solutions (b) and (c) in the testing of related substances in epirubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 1590

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

安全信息

• 象形图: GHS08,GHS07
• 警示用语：: Danger
• 危险声明: H302,H340,H350,H360FD
• 预防措施声明: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• 危险分类: Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B
• 储存分类代码: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable