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Merck

89397

Supelco

吉拉尔特试剂 T

for HPLC derivatization, LiChropur, 99.0-101.0% (AT)

别名:

(羧甲基)三甲基氯化铵酰肼, 乙酰肼三甲基氯化铵, 氯化三甲基铵乙酰肼

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About This Item

线性分子式:
[(CH3)3N+CH2CONHNH2]Cl-
CAS号:
分子量:
167.64
Beilstein:
3727163
EC號碼:
MDL號碼:
分類程式碼代碼:
12000000
PubChem物質ID:
NACRES:
NA.22

等級

for HPLC derivatization

品質等級

化驗

99.0-101.0% (AT)

形狀

crystals

品質

LiChropur

技術

HPLC: suitable

mp

188-192 °C (dec.) (lit.)

SMILES 字串

[Cl-].C[N+](C)(C)CC(=O)NN

InChI

1S/C5H13N3O.ClH/c1-8(2,3)4-5(9)7-6;/h4,6H2,1-3H3;1H

InChI 密鑰

YSULOORXQBDPCU-UHFFFAOYSA-N

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應用

Girard′s reagent T may be used as a derivatizing reagent for the determination of 5-Formyl-2′-deoxyuridine in cellular DNA samples using liquid chromatography–tandem mass spectrometry (LC–MS/MS) technique. Reducing saccharides can be derivatized by Girard′s reagent T and this can be analyzed by matrix-assisted laser desorption/ionization coupled to time of flight mass spectrometry (MALDI-TOF-MS) technique.

特點和優勢

  • Girard′s reagent T is a chemical derivatization reagent for LC-MS.
  • It has carbonyl functional group possessing high proton (cation) affinity that stabilizes a positive charge.       
  • It is commonly used in the derivatization of nucleosides.        
  • Derivatization reactions in mass spectrometry are used to improve ionization efficiency.
  • Derivatization can enhance precise quantitative analysis for profiling of relatively small analyte molecules, particularly in metabolomics.

推薦產品

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

法律資訊

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Oksana Lavrynenko et al.
Journal of lipid research, 54(8), 2265-2272 (2013-07-12)
Ecdysteroids are potent developmental regulators that control molting, reproduction, and stress response in arthropods. In developing larvae, picogram quantities of individual ecdysteroids and their conjugated forms are present along with milligrams of structural and energy storage lipids. To enhance the
Applications of MALDI-TOF Spectroscopy (2014)
Haizheng Hong et al.
Analytical chemistry, 79(1), 322-326 (2006-12-30)
Nucleoside 5-formyl-2'-deoxyuridine (FodU) is a major thymidine lesion generated by reactive oxygen species. In vitro and in vivo replication studies revealed that FodU can be mutagenic. A reliable and sensitive quantification method is, therefore, important for assessing the biological implications

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