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Merck

46648

Supelco

吡喹酮

VETRANAL®, analytical standard

别名:

2-(环己基羰基)-1,2,3,6,7-11b-六氢-4H-吡嗪并-[2,1-a]-异喹啉-4-酮

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250 MG
$105.00

$105.00


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250 MG
$105.00

About This Item

经验公式(希尔记法):
C19H24N2O2
CAS号:
分子量:
312.41
Beilstein:
761557
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

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等级

analytical standard

质量水平

产品线

VETRANAL®

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

抗生素抗菌谱

parasites

应用

clinical testing

包装形式

neat

作用机制

cell membrane | interferes

储存温度

2-8°C

SMILES字符串

O=C1CN(CC2N1CCc3ccccc23)C(=O)C4CCCCC4

InChI

1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2

InChI key

FSVJFNAIGNNGKK-UHFFFAOYSA-N

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一般描述

Chemical structure: quinolone
Praziquantel (PZQ) is a pyrazino-isoquinoline compound used as a broad-spectrum anthelmintic drug against trematode and cestode infections.[1][2]

应用

PZQ may be used as a reference standard for the determination for PZQ in:
  • Surface water samples by solid phase extraction (SPE) and ultra-high performance liquid chromatography-quadrupole linear ion trap tandem mass spectrometry (UHPLC-QqLIT-MS) equipped with electrospray ionization (ESI) source.[3]
  • Plants by HPLC with triple quadrupole mass spectrometry (HPLC-ESI-QqQ-MS/MS) operating in multiple reaction monitoring (MRM) mode.[4]
  • Tablet formulations[5][6] by reversed phase (RP) HPLC with ultraviolet (UV) detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律信息

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

危险声明

预防措施声明

危险分类

Aquatic Chronic 3

储存分类代码

11 - Combustible Solids

WGK

WGK 1

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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其他客户在看

Study of praziquantel phytoremediation and transformation and its removal in constructed wetland.
Marsik P, et al.
Journal of Hazardous Materials, 323, 394-399 (2017)
Analysis of anthelmintics in surface water by ultra high performance liquid chromatography coupled to quadrupole linear ion trap tandem mass spectrometry.
Zrncic M, et al.
Chemosphere, 99, 224-232 (2014)
Development and validation of a dissolution test method for albendazole and praziquantel in their combined dosage form.
Vignaduzzo S, et al.
Journal of the Brazilian Chemical Society, 26(4), 729-735 (2015)
Development and validation of an enantioselective LC-MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in human plasma, blood and dried blood spots.
Meister I, et al.
Journal of Pharmaceutical and Biomedical Analysis, 118, 81-88 (2016)
Malay Patra et al.
Journal of medicinal chemistry, 56(22), 9192-9198 (2013-11-14)
In vitro metabolic behavior was investigated for two chromium tricarbonyl derivatives of the antischistosomal drug praziquantel (PZQ) with the formula (η(6)-PZQ)Cr(CO)3 (1 and 2), by use of human liver microsomes. The metabolic profiles of the derivatives differ significantly. The optically

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