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Merck

01-6635

Sigma-Aldrich

氧化砷(III)

SAJ first grade, ≥99.0%

别名:

三氧化二砷, 亚砷酸

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About This Item

经验公式(希尔记法):
As2O3
CAS号:
分子量:
197.84
EC號碼:
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:

等級

SAJ first grade

蒸汽壓力

0.000001 hPa ( 66 °C)

化驗

≥99.0%

形狀

powder

存貨情形

available only in Japan

SMILES 字串

O=[As]O[As]=O

InChI

1S/As2O3/c3-1-5-2-4

InChI 密鑰

IKWTVSLWAPBBKU-UHFFFAOYSA-N

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訊號詞

Danger

危險分類

Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

標靶器官

Respiratory system,Cardio-vascular system,Gastrointestinal tract

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Cui Li et al.
Toxicology letters, 219(3), 223-230 (2013-04-02)
Arsenic trioxide (As2O3; ATO) is clinically effective in treating acute promyelocytic leukemia (APL); however, it frequently causes cardiotoxic effects. This study was designed to investigate whether ATO could induce apoptosis of cardiac fibroblasts (CFs) that play very important roles in
Masamitsu Yanada et al.
Blood, 121(16), 3095-3102 (2013-02-16)
The optimal treatments for relapsed acute promyelocytic leukemia (APL) remain equivocal. We conducted a phase 2 study to evaluate the efficacy and feasibility of a sequential treatment consisting of induction and consolidation with arsenic trioxide (ATO), peripheral blood stem cell
Yu-Chen Hu et al.
Biochemical pharmacology, 85(7), 1018-1026 (2013-01-23)
Arsenic trioxide (ATO) is widely used in tumor treatment, but excessive arsenic exposure can have adverse effects. We recently found that, in primary osteoblasts, ATO produces oxidative stress and causes DNA tailing, but does not induce apoptosis. We further examined
Yu-Hsun Lo et al.
Blood, 121(16), 3185-3194 (2013-02-23)
The functional activities of the tumor suppressor promyelocytic leukemia protein (PML) are mostly associated with its nuclear location. In the present study, we discovered an unexpected role of PML in NLRP3 inflammasome activation. In PML-deficient macrophages, the production of IL-1β
Yanfei Jia et al.
PloS one, 8(1), e54774-e54774 (2013-02-06)
Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC), represented by the production of AFP, has a more aggressive behavior than common gastric cancer. The underlying mechanisms are not well understood. Arsenic trioxide (As(2)O(3)) is used clinically to treat acute promyelocytic leukemia(APL) and has

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