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包裝
pkg of 2 × 10 mL
製造商／商標名
Roche
pH值
7.2-7.4 (20 °C)
應用
detection
儲存溫度
2-8°C
一般說明
TUNEL稀释缓冲液可与原位细胞死亡检测试剂盒一起使用。它可用于稀释特殊应用中TUNEL反应的末端脱氧核苷酸转移酶（TdT），还可标记DNA链断裂，从而在单细胞水平上检测和定量测定细胞和组织中的凋亡细胞死亡。
應用
TUNEL 稀释缓冲液已用于：
- 在制备TUNEL 关键商业检测用 TUNEL 反应混合物的过程中用于稀释末端脱氧核苷酸转移酶 dUTP 缺口末端标记 （TUNEL）酶 (TdT) [1]
- 定量测定大鼠肾脏中的细胞凋亡[2]
- 稀释末端脱氧核苷酸转移酶溶液，用于体外鉴定[3]
- TUNEL 测定用少突细胞的 DNA 片段化[4]
TUNEL稀释缓冲液已用于末端脱氧核苷酸转移酶dUTP缺口末端标记（TUNEL）测定。[5]
準備報告
工作浓度：结合物的工作浓度取决于应用和底物。
以下浓度为参考浓度：
储存条件（工作溶液）：TdT稀释液应在临用前配制，不可储存。
使用前，将TUNEL反应混合物一直放在冰上。
以下浓度为参考浓度：
- ELISA：100 mU/ml
- Western blot：100 mU/ml
储存条件（工作溶液）：TdT稀释液应在临用前配制，不可储存。
使用前，将TUNEL反应混合物一直放在冰上。
其他說明
仅用于生命科学研究。不可用于诊断。
訊號詞
Danger
危險聲明
危險分類
Aquatic Chronic 3 - Carc. 1B Inhalation
儲存類別代碼
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類（WGK）
WGK 2
閃點（°F）
does not flash
閃點（°C）
does not flash
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Nature cancer, 1(10), 976-989 (2020-10-20)
Oxidative phosphorylation (OXPHOS) defects caused by somatic mitochondrial DNA (mtDNA) mutations increase with age in human colorectal epithelium and are prevalent in colorectal tumours, but whether they actively contribute to tumorigenesis remains unknown. Here we demonstrate that mtDNA mutations causing
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Oncotarget, 8(41), 69493-69507 (2017-10-21)
Abemaciclib is an ATP-competitive, reversible kinase inhibitor selective for CDK4 and CDK6 that has shown antitumor activity as a single agent in hormone receptor positive (HR+) metastatic breast cancer in clinical trials. Here, we examined the mechanistic effects of abemaciclib
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