推荐产品
生物源
rat
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
473HD, monoclonal
物種活性
mouse
技術
immunohistochemistry: suitable
western blot: suitable
同型
IgMκ
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
一般說明
Anti-DSD-1 reacts with a glycosaminoglycan epitope selectively expressed on radial gliacytes of which a subpopulation shows stem cell properties. Cells isolated with this antibody from embryonic mouse tissue had multipotent characteristics and could turn into neurons, astrocytes and oligodendrocytes. The epitope is highly conserved and has been found in several vertebrates.
免疫原
Purified tissue fraction corresponding to mouse DSD-1.
應用
Anti-DSD-1 Antibody, clone 473HD is an antibody against DSD-1, clone 473HD for use in Western Blotting, Immunohistochemistry.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected DSD-1 in mouse hippocampus, mouse cerebellum, and mouse embryo tissue.
品質
Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected DSD-1 in 10 µg of mouse brain tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected DSD-1 in 10 µg of mouse brain tissue lysate.
標靶描述
~400 kDa observed
聯結
Replaces: MAB5790
外觀
Format: Purified
Purified rat monoclonal IgMκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
其他說明
Concentration: Please refer to lot specific datasheet.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Zaman Mirzadeh et al.
Nature metabolism, 1(2), 212-221 (2019-06-28)
In leptin-deficient ob/ob mice, obesity and diabetes are associated with abnormal development of neurocircuits in the hypothalamic arcuate nucleus (ARC)1, a critical brain area for energy and glucose homeostasis2,3. As this developmental defect can be remedied by systemic leptin administration
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