推荐产品
生物源
mouse
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
2A10, monoclonal
物種活性
mouse, human
技術
immunohistochemistry: suitable
western blot: suitable
輸入
sample type mesenchymal stem cell(s)
同型
IgG1κ
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... BMP7(655)
mouse ... Bmp7(12162)
一般說明
Bone morphogenetic protein-7 (BMP-7), also known as osteogenic protein-1, is a member of the TGF- superfamily, and is widely expressed during embryonic development. Like other members of the bone morphogenetic protein family, BMP-7 works synergistically with BMP-2 to play a key role in the differentiation of mesenchymal cells into bone and cartilage tissues by actively recruiting stem cells from the surrounding tissue, thereby initiating the bone formation cascade. In adult cells, BMP-7 is predominately expressed in the brain, kidneys, and bladder.
特異性
Reactivity with other species has not been tested.
應用
Immunohistochemistry: Recommended working dilution is 1:50.
Western Blotting: Recommended working concentration is 1 – 2 µg/mL.
Western Blotting: Recommended working concentration is 1 – 2 µg/mL.
This Anti-BMP-7 Antibody, clone 2A10 is validated for use in WB, IH for the detection of BMP-7.
標靶描述
46 kDa
外觀
Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4),
150 mM NaCl, and 0.05% sodium azide.
150 mM NaCl, and 0.05% sodium azide.
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Oral administration of recombinant adeno-associated virus-mediated bone morphogenetic protein-7 suppresses CCl(4)-induced hepatic fibrosis in mice.
Hao, ZM; Cai, M; Lv, YF; Huang, YH; Li, HH
Molecular Therapy null
Rongrong Zhang et al.
Communications biology, 7(1), 266-266 (2024-03-05)
Long noncoding RNA small nucleolar RNA host gene 5 (SNHG5) is an oncogene found in various human cancers. However, it is unclear what role SNHG5 plays in activating hepatic stellate cells (HSCs) and liver fibrosis. In this study, SNHG5 was
Ariadne Cristiane Cabral Cruz et al.
Journal of applied oral science : revista FOB, 27, e20180317-e20180317 (2019-02-28)
Bone morphogenetic protein type 2 (BMP-2) and retinoic acid (RA) are osteoinductive factors that stimulate endogenous mechanisms of bone repair which can be applied on management of osseous defects in oral and maxillofacial fields. Considering the different results of RA
Ariadne Cristiane Cabral Cruz et al.
Journal of applied oral science : revista FOB, 20(6), 628-635 (2013-01-19)
Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells. This study evaluated the effect of a recombinant BMP-2 as well as the
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