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HNDG4MAG-36K

Millipore

MILLIPLEX® Human Neurodegenerative Disease Magnetic Bead Panel 4 - Neuroscience Multiplex Assay

The analytes available for this multiplex kit are: Amyloid β40, Amyloid β42, GDNF, sRAGE, S100B.

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About This Item

UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.84
To order a Milliplex® kit, please search for your analyte of interest.
Design And Price Your Kit

质量水平

200

种属反应性

human

制造商/商品名称

Milliplex®

assay range

accuracy: 84-108%
standard curve range: 14-10,000 pg/mL
(S100B)
standard curve range: 21-15,000 pg/mL
(sRAGE)
standard curve range: 27-20,000 pg/mL
(Amyloid β42)
standard curve range: 3-2,500 pg/mL
(Amyloid β40)
standard curve range: 7-5,000 pg/mL
(GDNF)

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

wet ice

一般描述

The MILLIPLEX® Human Neurodegenerative Bead Panel 4 is to be used for the simultaneous quantification of the following 5 analytes in any combination in human cerebrospinal fluid (CSF): S100B, Amyloid β40 (Aβ1-40), Amyloid β42 (Aβ1-42), sRAGE, and GDNF. This kit is not validated for testing serum or cell culture supernatants.

Panel Type: Neuroscience

特异性

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

应用

  • Analytes: Amyloid β40, Amyloid β42, GDNF, sRAGE, S100B
  • Recommended Sample type: CSF
  • Recommended Sample dilution: 1:3
  • Assay Run Time: Overnight
  • Research Category: Neuroscience

特点和优势

Design your multiplex kit by choosing available analytes within this panel.

包装

Everything you need in a single kit.

储存及稳定性

Recommended storage for kit components is 2 - 8°C.

其他说明

Sensitivity: Refer to kit protocol for sensitivities of individual analytes.

法律信息

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形图

Skull and crossbonesEnvironment
GHS06,GHS09

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

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Nicholas J Justice et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(6), 2612-2623 (2015-02-13)
Recent studies have found that those who suffer from posttraumatic stress disorder (PTSD) are more likely to experience dementia as they age, most often Alzheimer's disease (AD). These findings suggest that the symptoms of PTSD might have an exacerbating effect

相关内容

Detection of Alzheimer’s Disease Biomarkers | MILLIPLEX® Assays

Learn how multiplex detection of Alzheimer’s disease biomarkers, using the MILLIPLEX® Human Amyloid Beta and Tau Magnetic Bead Panel, allows for a different perspective on neurodegenerative disease research.

Neuroscience Multiplex Assays | MILLIPLEX® Assays

Neuroscience multiplex assays, such as MILLIPLEX® multiplex assays, enable simultaneous measurement of neuroscience-related biomarkers to gain a better picture of neurodegenerative diseases, neurological disorders, and neuropeptide/neurohormone signaling.

Questions

1–2 of 2 Questions  

  1. Is the Milliplex Mouse Amyloid Beta Panel (MABMAG-83K) suitable for testing rat samples?

    1 answer

    1. Our R&D team conducted spike recovery and dilution linearity tests in rat serum samples. The sequence for both rat and mouse is identical. Although we attempted to develop this kit for both rat and mouse, the recovery in rats was considerably lower compared to mice. As a result, we do not recommend this kit for use with rats. Verification tests were not carried out in cerebrospinal fluid (CSF) or rat brain samples to assess potential improvement in recovery for other sample types.

      Helpful?

  2. What is the reason that GLP-1 total and active cannot be run together in HMHEMAG-34K?

    1 answer

    1. The same capture is used for both total and active GLP-1; however, the detection is specific to either total or active GLP-1.

      Helpful?

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