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一般描述
IgG is one of the most abundant protein in human serum. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.
特异性
Reacts with heavy chain of mouse IgG1, IgG2a, IgG2b and IgG3. Absorbed for mouse IgM and IgA, pooled human sera and purified human paraproteins. Minimal cross reactivity with human immunoglobulins.
The antibody reacts with the heavy chain of mouse IgG1, IgG2a, IgG2b and IgG3 as demonstrated by ELISA and flow cytometry. Minimal cross reactivity with human immunoglobulins.
免疫原
Epitope: IgG γ chain
Prepared from purified mouse IgG γ chain. Pooled antisera from goats hyperimmunized with mouse IgG paraproteins.
应用
Goat anti-Mouse IgG γ chain Antibody, Species Adsorbed detects level of Mouse IgG γ chain & has been published & validated for use in ELISA.
Research Category
Secondary & Control Antibodies
Secondary & Control Antibodies
Research Sub Category
Secondary Antibodies Adsorbed for Dual Labeling
Fragment Specific Secondary Antibodies
Secondary Antibodies Adsorbed for Dual Labeling
Fragment Specific Secondary Antibodies
外形
Affinity Chromatography
Format: Purified
Purified by affinity chromatography on pooled mouse IgG covalently linked to agarose. Liquid in 1.0 mL of 100 mM borate buffered saline, pH 8.2.
储存及稳定性
Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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警示用语：
Danger
危险声明
危险分类
Repr. 1B
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Atsushi Kawai et al.
The Journal of clinical investigation, 133(23) (2023-12-01)
Intranasal vaccines are anticipated to be powerful tools for combating many infectious diseases, including SARS-CoV-2, because they induce not only systemic immunity but also mucosal immunity at the site of initial infection. However, they are generally inefficient in inducing an
Eigo Kawahara et al.
Frontiers in immunology, 14, 1282016-1282016 (2024-01-04)
Respiratory syncytial virus (RSV) vaccines targeting the fusion glycoprotein (F protein) are highly effective clinically in preventing RSV challenges. The attachment glycoprotein (G protein) is a potentially effective vaccine antigen candidate, as it is important for cell adhesion during infection.
Marcus Estrada et al.
Human vaccines & immunotherapeutics, 20(1), 2315709-2315709 (2024-02-19)
NDV-HXP-S is a Newcastle disease virus (NDV) vectored vaccine candidate which expresses the S-antigen of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This vaccine candidate is under evaluation in human clinical studies with and without cytosine phosphate guanine (CpG) 1018®
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