ABT410

Anti-MATN3 Antibody

from rabbit, purified by affinity chromatography

• 别名: Matrilin-3
• UNSPSC代码: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物来源: rabbit
• 质量水平: 100
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 纯化方式: affinity chromatography
• 种属反应性: mouse
• 技术: immunocytochemistry: suitable; western blot: suitable
• UniProt登记号: O15232
• 运输: wet ice
• 靶向翻译后修饰: unmodified
• 基因信息: mouse ... Matn3(17182)

说明

一般描述

Matrilin-3 (MATN3) is a major component of the extracellular matrix of cartilage. MATNs are a family of non-collagenous extracellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.

免疫原

KLH-conjugated synthetic peptide corresponding to the C-terminus of human MATN3.

应用

Detect MATN3 using this Anti-MATN3 Antibody validated for use in western blotting & ICC.

Immunocytochemistry Analysis: 5 μg/mL from a representative lot detected MATN3 in NIH/3T3 cells.

质量

Evaluated by Western Blotting in NIH/3T3 cell lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected MATN3 in NIH/3T3 cell lysate.

目标描述

~52 kDa observed. Uncharacterized bands may be observed in some lysate(s).

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 2
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable