产品ABN1382监管中，请联系销售询价或购买 联系技术服务部门
推荐产品
生物源
rabbit
品質等級
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
mouse, human
技術
immunohistochemistry: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... DAGLA(747)
一般說明
The protein DGL-alpha is a lipase enzyme that catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG) endocannabinoid in tissues. Endocannabinoids are a group of lipid-like molecules that are neuromodulatory in nature and are involved in the control of many physiological functions including appetite, pain sensation, mood, and memory. They also mediate the psychoactive effects of cannabis (marijuana). Endocannabinoids (ECs) act as retrograde messengers that enable postsynaptic cells to regulate the strength of their synaptic inputs. DGL-alpha is also an excellent marker for cerebellum as DGL-alpha is highly expressed in cerebellum and necessary for the regulation of synaptic retrograde transmission in the cerebellum, hippocampus and striatum, as well as other regions including the auditory brainstem.
免疫原
Recombinant protein corresponding to the cytoplasmic domain of human DGL-α.
應用
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected DGL-α in human cerebellum and mouse cerebellum tissue.
Immunohistochemistry Analysis: A representative lot detected DGL-α in mouse brain tissue (Berghuis, P., et al. (2007). Science. 316:1212-1216).
Immunohistochemistry Analysis: A representative lot detected DGL-α in mouse brain tissue (Berghuis, P., et al. (2007). Science. 316:1212-1216).
This Anti-DGL-α Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of DGL-α.
品質
Evaluated by Western Blotting in mouse cerebellum tissue lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected DGL-α in 10 µg of mouse cerebellum tissue lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected DGL-α in 10 µg of mouse cerebellum tissue lysate.
標靶描述
~110 kDa observed. Uncharacterized band(s) may appear in some lysates.
其他說明
Concentration: Please refer to lot specific datasheet.
未找到合适的产品？
试试我们的产品选型工具.
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
B A S Reyes et al.
Neuroscience, 303, 323-337 (2015-07-15)
Endocannabinoids (eCBs) are involved in a myriad of physiological processes that are mediated through the activation of cannabinoid receptors, which are ubiquitously distributed within the nervous system. One neurochemical target at which cannabinoids interact to have global effects on behavior
Active Filters
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门
