推荐产品
产品名称
RyR-Calstabin Interaction Stabilizer, S107,
化驗
≥98% (HPLC)
品質等級
形狀
solid
製造商/商標名
Calbiochem®
儲存條件
OK to freeze
protect from light
顏色
off-white
溶解度
DMSO: 100 mg/mL
儲存溫度
2-8°C
SMILES 字串
S1CCN(Cc2c1ccc(c2)OC)C
InChI 密鑰
BGVCEGVSQDOGSB-UHFFFAOYSA-N
一般說明
RyR-Calstabin Interaction Stabilizer, S107 can protect hippocampal neurons from GABAergic synaptic changes caused by Abeta42 oligomers.[1]
應用
RyR-Calstabin Interaction Stabilizer, S107 has been used in culture media for hypoxic exposures to study the impact of hypoxia on sarcoplasmic reticulum calcium leakage and expression of ryanodine receptor2 (RyR2).[2]
生化/生理作用
Primary Target
RyR2
RyR2
包裝
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
重構
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他說明
Please note that the molecular weight for this compound is batch-specific due to variable water content. Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight. The molecular weight provided represents the baseline molecular weight without water.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
The ryanodine receptor-calstabin interaction stabilizer S107 protects hippocampal neurons from GABAergic synaptic alterations induced by Abeta42 oligomers
Hidisoglu E, et al.
The Journal of Physiology, 600(24), 5295-5309 (2022)
Hypoxia-Induced Sarcoplasmic Reticulum Ca2+ Leak Is Reversed by Ryanodine Receptor Stabilizer JTV-519 in HL-1 Cardiomyocytes
Trinh MD, et al.
Anatolian journal of cardiology, 26(6), 476-476 (2022)
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