推荐产品
方案
≥97% (SDS-PAGE)
质量水平
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
杂质
<1.0 EU/μg protein Endotoxin
运输
ambient
储存温度
−20°C
一般描述
Recombinant, mouse insulin-like growth factor II (IGF-II) consisting of amino acids 25-91 and expressed in E. coli. Mouse IGF-II is synthesized as a 180 amino acid preproprecursor. Mature IGF-II is 91% and 97% amino acid identical to human and rat IGF-II, respectively.
生化/生理作用
ED₅₀ = 2-10 ng/ml as measured in a serum-free cell proliferation assay using MCF-7 human breast adenocarcinoma cells.
警告
Toxicity: Standard Handling (A)
外形
Lyophilized from 0.2 µm sterile-filtered Acetonitrile, TFA.
重悬
Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Reconstitute to 100 µg/ml in sterile PBS.
其他说明
Ostrovsky, O., et al. 2009. Mol. Biol. Cell20, 1855.
Chao, W. & P. A. DAmore, 2008. Cytokine Growth Factor Rev.19, 111.
Belfiore, A., 2007. Curr. Pharm. Des.13, 671.
Cornish, J., et al. 2007. Am. J. Physiol. Endocrinol. Metab.292,E117.
Merrick, D., et al. 2007. BMC Dev. Biol.7, 65.
Pavelic, J., et al. 2007. Indian J. Med. Res.125, 511.
VarelaNieto, I., et al. 2007. Curr. Pharm. Des.13,687.
Denley, A. et al. 2005. Cytokine Growth Factor Re,v.16, 421.
LeRoith, D. & C.T. Roberts Jr., 2003. Cancer Lett.195,127.
Buchanan, C.M., et al. 2001. Biochem. J.360, 431.
Werner, H. & D. LeRoith, 2000. Cell. Mol. Life Sci.57, 932.
Goya, L., et al. 1999. J. Biol. Chem.274 24633.
Daughaday, W.H., et al. 1993. Proc. Natl. Acad. Sci. USA90, 5823.
Holthuizen, P.E., et al. 1993. Regul. Pept.48, 77.
McCarthy, T.L., et al. 1992. Endocrinology130, 1303.
Zindy, F., et al. 1992. J. Hepatol.14, 30.
Rotwein, P. & L.J. Hall, 1990. DNA Cell Biol.10,725.
Rotwein, P., et al. 1988. Proc. Natl. Acad. Sci. USA85, 265.
Stempien, M.M., et al. 1986. DNA5, 357.
Chao, W. & P. A. DAmore, 2008. Cytokine Growth Factor Rev.19, 111.
Belfiore, A., 2007. Curr. Pharm. Des.13, 671.
Cornish, J., et al. 2007. Am. J. Physiol. Endocrinol. Metab.292,E117.
Merrick, D., et al. 2007. BMC Dev. Biol.7, 65.
Pavelic, J., et al. 2007. Indian J. Med. Res.125, 511.
VarelaNieto, I., et al. 2007. Curr. Pharm. Des.13,687.
Denley, A. et al. 2005. Cytokine Growth Factor Re,v.16, 421.
LeRoith, D. & C.T. Roberts Jr., 2003. Cancer Lett.195,127.
Buchanan, C.M., et al. 2001. Biochem. J.360, 431.
Werner, H. & D. LeRoith, 2000. Cell. Mol. Life Sci.57, 932.
Goya, L., et al. 1999. J. Biol. Chem.274 24633.
Daughaday, W.H., et al. 1993. Proc. Natl. Acad. Sci. USA90, 5823.
Holthuizen, P.E., et al. 1993. Regul. Pept.48, 77.
McCarthy, T.L., et al. 1992. Endocrinology130, 1303.
Zindy, F., et al. 1992. J. Hepatol.14, 30.
Rotwein, P. & L.J. Hall, 1990. DNA Cell Biol.10,725.
Rotwein, P., et al. 1988. Proc. Natl. Acad. Sci. USA85, 265.
Stempien, M.M., et al. 1986. DNA5, 357.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2
储存分类代码
4.1B - Flammable solid hazardous materials
WGK
WGK 2
Active Filters
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