Met D1246N is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). In vitro studies have demonstrated enhanced kinase activity from this mutant.
N-terminal 6His-tagged, recombinant, human, Met amino acids 974-end, containing the mutation D1246N
Product Source: expressed by baculovirus in Sf21 insect cells
生化/生理作用
Protein Target: Met
Target Sub-Family: TK
包装
Available in 250 μg --call for pricing and availability and reference catalog number 14-818M when ordering the 250 μg size.
外形
Ni2+/NTA-agarose
储存及稳定性
6 months at -70°C
其他说明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
