(For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
分子量
Mw 35.5 kDa
纯化方式
(Ni2+/NTA-agarose)
种属反应性
human
制造商/商品名称
Upstate®
技术
activity assay: suitable (kinase)
登记号
(FUNCTION: SwissProt: Q05397 # Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. ) NM_005607.3
N-terminal 6His-tagged, recombinant, human FAK, amino acids 411-686
生化/生理作用
Protein Target: FAK
包装
Also available in 10 μg size and in bulk
质量
routinely evaluated by phosphorylation of 100μM substrate peptide (EEEEYEEEEEEYYIIEEEEEEYEEEEEEYYEEEEEEKKK)
目标描述
FAK
其他说明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
