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Merck
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文件

14-627-M

Sigma-Aldrich

EGFR (L861Q) Protein, active, 10 µg

Active, N-terminal GST-tagged, recombinant human EGF Receptor, amino acids 696-end containing the mutation L861Q, for use in Enzyme Assays.

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About This Item

分類程式碼代碼:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物源

human

品質等級

100
300

重組細胞

expressed in baculovirus infected Sf21 cells

分子量

Mw 85.8 kDa

製造商／商標名

Upstate®

技術

activity assay: suitable

NCBI登錄號

NM_005228.3
NM_201282.1
NM_201283.1
NM_201284.1

UniProt登錄號

P00533

一般說明

N-terminal GST-tagged, recombinant human EGF Receptor, amino acids 696-end containing the mutation L861Q
Product Source: baculovirus in Sf21 insect cells

應用

Research Category
Inflammation & Immunology

生化／生理作用

Protein Target: EGFR
Target Sub-Family: TK

品質

routinely evaluated by phosphorylation of 0.1mg/ml Poly (Glu4-Tyr)

外觀

Glutathione-agarose

儲存和穩定性

6 months at -70°C

其他說明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H317

危險分類

Skin Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Thomas J Lynch et al.
The New England journal of medicine, 350(21), 2129-2139 (2004-05-01)
Most patients with non-small-cell lung cancer have no response to the tyrosine kinase inhibitor gefitinib, which targets the epidermal growth factor receptor (EGFR). However, about 10 percent of patients have a rapid and often dramatic clinical response. The molecular mechanisms

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