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生物源
mouse
品質等級
100
300
分子量
Mw 67.7 kDa
製造商／商標名
Upstate®
技術
activity assay: suitable (kinase)
NCBI登錄號
UniProt登錄號
基因資訊
mouse ... MAP2K4(26398)
一般說明
N-terminal GST tagged, murine MKK4 residues 34-end
Product Source: expressed in E. coli
生化／生理作用
Protein Target: MKK4
Target Sub-Family: STE
包裝
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-377M when ordering the 250 µg size.
品質
routinely evaluated by phosphorylation of ATF2 substrate
外觀
Purified using glutathione agarose. Activated by incubation with MEKK and then re-purified using Ni2+/NTA agarose
儲存和穩定性
6 months at -70C
其他說明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
訊號詞
Warning
危險聲明
危險分類
Skin Sens. 1
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Y Fleming et al.
The Biochemical journal, 352 Pt 1, 145-154 (2000-11-04)
Stress-activated protein kinase 1 (SAPK1), also called c-Jun N-terminal kinase (JNK), becomes activated in vivo in response to pro-inflammatory cytokines or cellular stresses. Its full activation requires the phosphorylation of a threonine and a tyrosine residue in a Thr-Pro-Tyr motif
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