推荐产品
生物源
rabbit
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
mouse, human, rat
製造商／商標名
Upstate®
技術
western blot: suitable
同型
IgG
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
mouse ... Lingo1(235402)
特異性
LINGO-1
免疫原
KLH-conjugated, synthetic peptide corresponding to amino acid residues 611-620 of human LINGO-1 (APRKFNMKMI)
應用
Detect LINGO-1 using this Anti-LINGO-1 Antibody validated for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
品質
routinely evaluated by immunoblot on mouse brain membrane samples.
標靶描述
Mr ~83kDa
外觀
Protein A purified
Format: Purified
儲存和穩定性
stable for 2 years at -20°C from date of shipment
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
Alexandra Trifunovski et al.
Neuroreport, 15(15), 2397-2400 (2005-01-11)
Axonal regeneration after injury can be limited in the adult CNS by the presence of inhibitory proteins such as Nogo. Nogo binds to a receptor complex that consists of Nogo receptor (NgR), p75NTR, and Lingo-1. Nogo binding activates RhoA, which
From cell death to neuronal regeneration, effects of the p75 neurotrophin receptor depend on interactions with partner subunits.
Bandtlow, Christine and Dechant, Georg
Science's STKE : Signal Transduction Knowledge Environment, 2004, pe24-pe24 (2004)
Multi-tasking by the p75 neurotrophin receptor: sortilin things out?
Bronfman, Francisca C and Fainzilber, Mike
EMBO Reports, 5, 867-871 (2004)
TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions.
J Satoh, H Tabunoki, T Yamamura, K Arima, H Konno
Neuropathology and Applied Neurobiology null
Sha Mi et al.
Nature neuroscience, 7(3), 221-228 (2004-02-18)
Axon regeneration in the adult CNS is prevented by inhibitors in myelin. These inhibitors seem to modulate RhoA activity by binding to a receptor complex comprising a ligand-binding subunit (the Nogo-66 receptor NgR1) and a signal transducing subunit (the neurotrophin
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