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生物源
rabbit
品質等級
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
bovine, rat, human, mouse
製造商／商標名
Upstate®
技術
western blot: suitable
同型
IgG
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... PPP2CA(5515)
特異性
PP2A催化亚基
免疫原
对应于人PP2A氨基酸290-304（DPAPRRGEPHVTRRT）的肽
應用
研究子类别
氧化应激
神经退行性疾病
氧化应激
神经退行性疾病
研究类别
信号传导
神经科学
信号传导
神经科学
该抗-PP2A抗体（C亚基）经过验证可用于WB检测PP2A。
品質
已通过免疫印迹对小鼠脑、心脏、睾丸和肾脏匀浆液的RIPA裂解液进行常规评估
標靶描述
36kDa
外觀
0.2M Tris-甘氨酸（pH 7.4）、0.15M NaCl、0.05％叠氮化钠、5mg/ml BSA，然后添加甘油至30％
免疫亲和层析
儲存和穩定性
在-20°C下可保存2年
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
Satoru Kake et al.
Scientific reports, 7(1), 4279-4279 (2017-06-29)
Canine mammary tumor is the most common neoplasm in female dogs, and it has generated considerable attention as a translational model for human breast cancer. Ser/Thr protein phosphatase 2A (PP2A) plays a critical role as a tumor suppressor, and SET/I2PP2A
Characterization of SET/I2PP2A isoforms in dogs.
Yabe, R; Fujiwara, N; Mizuno, T; Usui, T; Ohama, T; Sato, K
The Journal of Veterinary Medical Science null
Shunya Tsuji et al.
The Journal of veterinary medical science, 81(10), 1424-1430 (2019-09-19)
Osteosarcoma (OSA) is the most common bone tumor in dogs. Protein phosphatase 2A (PP2A), an evolutionary conserved serine/threonine protein phosphatase, is a crucial tumor suppressor. SET is a PP2A inhibitory protein that directly interacts with PP2A and suppresses its phosphatase
Rongbin Hu et al.
Plant, cell & environment, 40(1), 150-164 (2016-10-28)
Protein phosphatase 2A (PP2A) is an enzyme consisting of three subunits: a scaffolding A subunit, a regulatory B subunit and a catalytic C subunit. PP2As were shown to play diverse roles in eukaryotes. In this study, the function of the
Sana Ando et al.
The Journal of biological chemistry, 300(5), 107277-107277 (2024-04-09)
Protein phosphatase 2A (PP2A) is an essential serine/threonine protein phosphatase, and its dysfunction is involved in the onset of cancer and neurodegenerative disorders. PP2A functions as a trimeric holoenzyme whose composition is regulated by the methyl-esterification (methylation) of the PP2A
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