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Merck
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文件

06-1091

Sigma-Aldrich

Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2)

from rabbit, purified by affinity chromatography

别名:

interleukin 13 receptor, alpha 2, interleukin-13 receptor subunit alpha-2, interleukin 13 receptor alpha 2 chain, Interleukin-13-binding protein, IL-13R subunit alpha-2, cancer/testis antigen 19, IL-13 receptor subunit alpha-2, interleukin 13 binding pro

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

human

技術

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... IL13RA2(3598)

一般說明

Interleukin-13 receptor subunit alpha-2 (IL-13RA2) is one receptor of Interleukin-13 which is a key moderator of asthma and allergic inflammation. IL-13 and its receptors have been shown to play a part in alcohol-mediated activation of pro-fibrotic pathways. IL-13 has a suppressive effect on macrophage activation but cannot activate T cells.

特異性

This antibody recognizes Interleukin-13 receptor, alpha-2 at the cytoplasmic domain.

免疫原

Epitope: Cytoplasmic Domain
KLH-conjugated linear peptide corresponding to human Interleukin-13 receptor, alpha-2 at the cytoplasmic domain.

應用

Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2) is an antibody against IL-13 receptor for use in WB, IH(P).
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
Western Blot (SNAP i.d. Protein Detection System) Analysis: 5 µg/mL from a previous lot detected Interleukin-13 receptor, alpha-2 in 10 µg of HeLa cell lysate.

Immunohistochemistry (paraffin) Analysis: A 1:500 dilution from a previous lot was used to detect Interleukin-13 receptor, alpha-2 in colorectal carcinoma and normal human kidney/medulla tissue sections.

品質

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Interleukin-13 receptor, alpha-2 in 10 µg of HeLa cell lysate.

標靶描述

~44 kDa observed

外觀

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
HeLa cell lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Yang Zhou et al.
The Journal of clinical investigation, 125(8), 3178-3192 (2015-06-30)
Hermansky-Pudlak syndrome (HPS) comprises a group of inherited disorders caused by mutations that alter the function of lysosome-related organelles. Pulmonary fibrosis is the major cause of morbidity and mortality in patients with subtypes HPS-1 and HPS-4, which both result from

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