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Merck
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T-032

Supelco

(−)-Δ8-四氢大麻酚标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式（希尔记法）:
C21H30O2
CAS号:
5957-75-5
分子量:
314.46
EC號碼:
200-659-6
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商／商標名

Cerilliant®

drug control

Narcotic Licence Schedule D (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

濃度

1.0 mg/mL in methanol

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

cannabis testing
cannabis testing

格式

single component solution

儲存溫度

−20°C

InChI

1S/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9,12-13,16-17,22H,5-8,10-11H2,1-4H3

InChI 密鑰

HCAWPGARWVBULJ-UHFFFAOYSA-N

相关类别

一般說明

认证溶液标准品适用于大麻素测试、临床毒理学、法医分析或尿液药物测试的LC/MS或GC/MS应用。Δ8-THC是合成THC生产工艺中的杂质。Δ8-THC 是大麻主要精神活性成分（称为 Δ9-四氢大麻酚）的双键异构体。这种大麻素具有止吐、抗焦虑、刺激食欲和镇痛作用。

應用

这种认证的峰值溶液® 适用于通过 HPLC、GC/MS 或 LC-MS/MS 进行 (−)-Δ8-THC 测试，从而用于法医分析、临床毒理学、尿液药物测试和大麻效力或杂质分析测试等应用。该认证标准物质（CRM）还可作如下用途：
  • 根据国际药品注册协调会议（ICH）分析方法验证三方指南，通过 HPLC-UV 方法对不同大麻品种的生物质和提取物中的 11 种大麻素进行多重分析
  • 使用等度高效液相色谱（HPLC）结合二极管阵列检测器（DAD）分离和估算不同大麻产品中的 13 种大麻素
  • 使用气相色谱-质谱（GC-MS）分析硅烷化和酯化衍生后从大麻花序中提取的 10 种主要大麻素
  • 使用超高效液相色谱（UHPLC）结合三重四极杆质谱法在液-液萃取后定量测定人血浆样品中的大麻二酚和 Δ9-四氢大麻酚，以及鉴定少量大麻素
  • 基于 QuEChERS 提取 20 种食品样品中的 15 种大麻素，然后通过液相色谱-串联质谱法（LC-MS/MS）定量

特點和優勢

  • 完全符合 ISO/IEC 17025 和 ISO 17034 认证
  • 附综合分析证书（CoA），包括稳定性、均匀性、浓度准确性、不确定性和可追溯性数据
  • 通过实时稳定性研究严格测试，以确保准确性和保质期
  • 使用合格的精密天平进行重量准备，以确保最小不确定性
  • 氩气环境下火焰密封，装入安瓿以便长期保存
  • 提供方便的 DEA 豁免格式，以提高实验室效率

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

51.8 °F - closed cup

閃點（°C）

11.0 °C - closed cup

分析证书(COA)

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S H Burstein et al.
Life sciences, 56(23-24), 1991-1998 (1995-01-01)
Binding and photoactivation of a cannabinoid-derived ligand to intact mouse peritoneal cells has resulted in the labelling of a G-protein gamma-subunit. The assignment of structure is based on the product's physical characteristics and its ability to react with a polyclonal
S Muchtar et al.
Ophthalmic research, 24(3), 142-149 (1992-01-01)
delta 8-Tetrahydrocannabinol (delta 8-THC), a known antiglaucoma lipophilic drug, was incorporated in a submicron emulsion for ocular administration. The mean droplet size of the emulsion was 130 +/- 41 nm, and no droplet was larger than 400 nm. No change
J W Huffman et al.
Life sciences, 56(23-24), 2021-2024 (1995-01-01)
The synthesis of (2'RS)-2'-methyl-, (3'RS)-, (3'S)-3'-methyl-, and 4'-methyl-delta 8-THC has been carried out, and the pharmacology of all four compounds has been investigated. All four compounds showed typical cannabinoid activity both in vitro and in vivo. The 2'-methyl compound is
Abir T El-Alfy et al.
Pharmacology, biochemistry, and behavior, 95(4), 434-442 (2010-03-25)
The antidepressant action of cannabis as well as the interaction between antidepressants and the endocannabinoid system has been reported. This study was conducted to assess the antidepressant-like activity of Delta(9)-THC and other cannabinoids. Cannabinoids were initially evaluated in the mouse
Donna A Whyte et al.
Pharmacology, 85(6), 328-335 (2010-06-03)
The primary cannabinoids, Delta(9)-tetrahydrocannabinol (Delta(9)-THC) and Delta(8)-tetrahydrocannabinol (Delta(8)-THC) are known to disturb the mitochondrial function and possess antitumor activities. These observations prompted us to investigate their effects on the mitochondrial O(2) consumption in human oral cancer cells (Tu183). This epithelial
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