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Merck

LM2144

Avanti

Sphingosine-1-Phosphate (d17:1)

Avanti Research - A Croda Brand

别名:

heptadeca-sphing-4-enine-1-phosphate

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About This Item

经验公式(希尔记法):
C17H36NO5P
分子量:
365.45
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

ethanol solution

包裝

pkg of 1 × 1 mL (LM2144-1EA)

製造商/商標名

Avanti Research - A Croda Brand

濃度

~10 μg/mL (Refer to C of A for lot specific concentration.)

應用

lipidomics
metabolomics

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

CCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@]([NH3+])([H])COP([O-])(O)=O

InChI

1S/C17H36NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(19)16(18)15-23-24(20,21)22/h13-14,16-17,19H,2-12,15,18H2,1H3,(H2,20,21,22)/b14-13+/t16-,17+/m0/s1

InChI 密鑰

VITGNIYTXHNNNE-LHMZYYNSSA-N

相关类别

一般說明

Sphingosine-1-phosphate (S1P) is a sphingolipid found in yeast, plants and mammals and is produced in endothelial cells. It is a cellular metabolite and signalling lipid in mammalian cells. S1P is synthesized by sphingosine kinases from sphingosine. It is a high affinity ligand for sphingosine-1-phosphate receptor (S1P1-5).

生化/生理作用

Sphingosine 1-phosphate (S1P) plays a vital role as a secondary messenger in physiological processes. It is implicated in the pathogenesis of osteoporosis, cancer, atherosclerosis and diabetes. S1P regulates skin dendritic cells and keratinocytes

包裝

2 mL Amber Glass Sealed Ampule (LM2144-1EA)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

FlameExclamation mark

訊號詞

Danger

危險聲明

危險分類

Eye Irrit. 2 - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

55.4 °F - closed cup

閃點(°C)

13.0 °C - closed cup


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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访问文档库

Sphingosine-1-phosphate: an enigmatic signalling lipid
Spiegel S and Milstien S
Nature Reviews in Molecular and Cell Biology, 4(5), 397-397 (2003)
Sphingosine-1-phosphate as signaling molecule in the skin
Japtok L, et al.
Allergo journal international, 23(2), 54-59 (2014)
High-Throughput Assays to Measure Intracellular Ca2+ Mobilization in Cells that Express Recombinant S1P Receptor Subtypes
Valentine WJ and Tigyi G
Methods in Molecular Biology, 77-87 (2012)
Sphingosine-1-phosphate signaling and its role in disease
Maceyka M, et al.
Trends in Cell Biology, 22(1), 50-60 (2012)

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