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表单
powder
包装
pkg of 1 × 100 mg (860547P-100mg)
pkg of 1 × 25 mg (860547P-25mg)
pkg of 1 × 5 mg (860547P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
脂质类型
sphingolipids
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O
InChI
1S/C42H81NO8/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-38(46)43-35(34-50-42-41(49)40(48)39(47)37(33-44)51-42)36(45)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h29,31,35-37,39-42,44-45,47-49H,3-28,30,32-34H2,1-2H3,(H,43,46)/b31-29+/t35-,36+,37?,39+,40?,41?,42+/m0/s1
InChI key
YMYQEDCYNANIPI-KNSMPFANSA-N
应用
C18 Glucosyl(β) Ceramide (d18:1/18:0) or D-glucosyl-β-1,1′-N-stearoyl-D-erythro-sphingosine has been used:
- as a lipid standard for its quantification using differential ion mobility spectrometry (DMS) coupled with liquid chromatography in electrospray ionization tandem mass spectrometry (LC-ESI-DMS-MS/MS) in human plasma[1]
- in the preparation of lipid dispersions[2]
- used in an assay to monitor the turnover of glucosylceramide in glucocerebrosidase (GBA1) cell free system[3]
包装
5 mL Amber Glass Screw Cap Vial (860547P-100mg)
5 mL Amber Glass Screw Cap Vial (860547P-25mg)
5 mL Amber Glass Screw Cap Vial (860547P-5mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
通常也和此产品一起购买
产品编号
说明
价格
储存分类代码
11 - Combustible Solids
其他客户在看
Jong Hoon Won et al.
Neuroscience, 427, 1-15 (2019-11-26)
Neurotransmitter release is mediated by ceramide, which is generated by sphingomyelin hydrolysis. In the present study, we examined whether synaptosomal-associated protein 25 (SNAP-25) is involved in ceramide production and exocytosis. Neutral sphingomyelinase 2 (nSMase2) was partially purified from bovine brain
Differential mobility spectrometry as an orthogonal separation to LC-ESI-MS/MS for quantification of isomeric cerebrosides in plasma and cerebrospinal fluid
Xu H, et al.
Journal of Lipid Research, jlr-D089797 (2018)
Joseph R Mazzulli et al.
Cell, 146(1), 37-52 (2011-06-28)
Parkinson's disease (PD), an adult neurodegenerative disorder, has been clinically linked to the lysosomal storage disorder Gaucher disease (GD), but the mechanistic connection is not known. Here, we show that functional loss of GD-linked glucocerebrosidase (GCase) in primary cultures or
Hongbin Xu et al.
Journal of lipid research, 60(1), 200-211 (2018-11-11)
Cerebrosides, including glucosylceramides (GlcCers) and galactosylceramides (GalCers), are important membrane components of animal cells with deficiencies resulting in devastating lysosomal storage disorders. Their quantification is essential for disease diagnosis and a better understanding of disease mechanisms. The simultaneous quantification of
Zdenek Berger et al.
PloS one, 10(3), e0119141-e0119141 (2015-03-13)
Mutations in glucocerebrosidase (GBA1) cause Gaucher disease and also represent a common risk factor for Parkinson's disease and Dementia with Lewy bodies. Recently, new tool molecules were described which can increase turnover of an artificial substrate 4MUG when incubated with
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