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Merck

850181P

Avanti

08:0 PI

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

别名:

PI(8:0/8:0)

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About This Item

经验公式(希尔记法):
C25H50NO13P
分子量:
603.64
分類程式碼代碼:
51191904
NACRES:
NA.25
价格与库存信息目前不能提供

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 100 μg (with stopper and crimp cap (850181P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850181P-500ug))

製造商/商標名

Avanti Research - A Croda Brand 850181P

脂質類型

phospholipids
cardiolipins

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+]

InChI

1S/C25H47O13P.H3N/c1-3-5-7-9-11-13-18(26)35-15-17(37-19(27)14-12-10-8-6-4-2)16-36-39(33,34)38-25-23(31)21(29)20(28)22(30)24(25)32;/h17,20-25,28-32H,3-16H2,1-2H3,(H,33,34);1H3/t17-,20-,21-,22+,23-,24-,25-;/m1./s1

InChI 密鑰

BJQNDQRSJKQZAM-RGISUMIPSA-N

一般說明

磷脂酰肌醇(PI)是一种甘油磷脂,具有带有环己醇部分的头基。[1]08:1 PI(1,2-二辛酰基-sn-甘油-3-磷酸-(1′-肌醇))是具有较短酰基链的PI类似物。[2]

應用

08:0 PI(1,2-二辛酰基-sn-甘油-3-磷酸-(1′-肌醇))可以用于:
  • 作为磷脂酰-肌醇甘露糖基转移酶(PimA)的底物来比较非底物磷脂对活性的效应[2]
  • 在酶促测定中替代分枝杆菌膜以测量PimA活性[2]
  • 作为离子阱飞行时间(IT-TOF)系统中的磷脂(PL)标准品,以研究独特PL的断裂原理,也用作坚果样品中PL定量分析的非内源PL标准品[3]

生化/生理作用

磷脂酰肌醇(PI)充当磷酸肌醇(一类信号脂质)的前体。[4]
肌醇磷脂物质是膜结合的信号分子,它参与细胞生理学的几乎所有方面,包括细胞生长、代谢、增殖和存活。

包裝

带塞子和压接盖的2 mL棕色血清瓶(850181P-100ug)
带塞子和压接盖的2 mL棕色血清瓶(850181P-500ug)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

閃點(°F)

No data available

閃點(°C)

No data available


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Marcelo E Guerin et al.
The Journal of biological chemistry, 282(28), 20705-20714 (2007-05-19)
Mycobacterial phosphatidylinositol mannosides (PIMs) and metabolically derived cell wall lipoglycans play important roles in host-pathogen interactions, but their biosynthetic pathways are poorly understood. Here we focus on Mycobacterium smegmatis PimA, an essential enzyme responsible for the initial mannosylation of phosphatidylinositol.
Inhibition of Phosphoinositide 3-Kinase and Acquired Long QT Syndrome
Cardiac Electrophysiology: From Cell to Bedside, 106-112 (2018)
Endocytosis and the Endosomal Membrane System
Cell Biology, 377-392 (2017)
Shuang Song et al.
Food chemistry, 240, 1171-1178 (2017-09-28)
Nuts, a class of fatty natural food, are associated with a series of health benefit. Lipid, which is the most abundant nutrient in nuts, could be one of the major contributors to many beneficial effects. In previous studies, only the
Zhen Chen et al.
Theriogenology, 144, 56-66 (2020-01-10)
A comparative lipidomic profiling analysis of dairy cattle oocytes with different developmental competences was performed using a combination of high performance liquid chromatography-high resolution tandem mass spectrometry and multivariate statistical analysis. Significant lipidomic changes were identified in degenerating oocytes. Total

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