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840028P

Avanti

17:0 PS

Avanti Research™ - A Croda Brand

别名:

PS(17:0/17:0)

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About This Item

经验公式（希尔记法）:
C40H77NO10PNa
CAS号:
799268-51-2
分子量:
786.00
UNSPSC代码:
51191904
NACRES:
NA.25
价格与库存信息目前不能提供

描述

1,2-diheptadecanoyl-sn-glycero-3-phospho-L-serine (sodium salt)

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 10 mg (840028P-10mg)
pkg of 1 × 25 mg (840028P-25mg)

制造商/商品名称

Avanti Research™ - A Croda Brand

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C40H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-38(42)48-33-36(34-49-52(46,47)50-35-37(41)40(44)45)51-39(43)32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h36-37H,3-35,41H2,1-2H3,(H,44,45)(H,46,47);/q;+1/p-1/t36-,37+;/m1./s1

InChI key

HNPCQASYRKKJRQ-JBEIVTSCSA-M

一般描述

磷脂酰丝氨酸（PtdSer）是阴离子磷脂，大量存在于真核细胞内。10%的总细胞脂质由磷脂酰丝氨酸组成。[1]O-磷酸-L-丝氨酸是对热稳定的底物。[2]

应用

17：0 Ps用作内标，用于BXD肝脏[3]和血浆样品分析。 [4] 也可作为标准品，通过液相色谱-串联质谱，评估酿酒酵母细胞脂质组。[5]

生化/生理作用

磷脂酰丝氨酸（PtdSer）参与细胞内各种信号通路。同时在细胞凋亡和血液凝结中起主要作用。[1]

包装

5 mL棕色玻璃螺旋盖样品瓶（840028P-10mg）
5 mL棕色玻璃螺旋盖样品瓶（840028P-25mg）

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Karamat Mohammad et al.
Journal of visualized experiments : JoVE, (157) (2020-03-24)
Lipids are structurally diverse amphipathic molecules that are insoluble in water. Lipids are essential contributors to the organization and function of biological membranes, energy storage and production, cellular signaling, vesicular transport of proteins, organelle biogenesis, and regulated cell death. Because
Koshiki Mino et al.
FEBS letters, 551(1-3), 133-138 (2003-09-11)
O-Acetylserine sulfhydrylase (OASS), a pyridoxal 5'-phosphate (PLP)-dependent enzyme, catalyzes the synthesis of L-cysteine from O-acetyl-L-serine and sulfide. O-Acetyl-L-serine is labile at high temperatures at which hyperthermophilic archaea live. Herein, a study of the substrate specificity of OASS from Aeropyrum pernix
Emily L Gill et al.
Journal of proteome research, 19(1), 424-431 (2019-11-13)
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the brain, as well as the degeneration of motor and nonmotor circuitries. The cause of neuronal death is currently unknown, although chronic
Rose M Gathungu et al.
Analytical chemistry, 90(22), 13523-13532 (2018-09-29)
Lipidomics requires the accurate annotation of lipids in complex samples to enable determination of their biological relevance. We demonstrate that unintentional in-source fragmentation (ISF, common in lipidomics) generates ions that have identical masses to other lipids. Lysophosphatidylcholines (LPC), for example
Jason G Kay et al.
Cell communication and signaling : CCS, 17(1), 126-126 (2019-10-17)
Phosphatidylserine (PtdSer), an essential constituent of eukaryotic membranes, is the most abundant anionic phospholipid in the eukaryotic cell accounting for up to 10% of the total cellular lipid. Much of what is known about PtdSer is the role exofacial PtdSer
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