840012C

Heart CA

Avanti Research^™ - A Croda Brand

• 别名: Cardiolipin (Heart, Bovine) (sodium salt)
• CAS号: 383907-10-6
• MDL编号: MFCD11974098
• UNSPSC代码: 12352211
• NACRES: NA.25

属性

• 方案: >99% (TLC)
• 表单: liquid
• 包装: pkg of 1 × 2 mL (840012C-50mg); pkg of 1 × 2.5 mL (840012C-25mg); pkg of 1 × 4 mL (840012C-100mg)
• 制造商/商品名称: Avanti Research^™ - A Croda Brand
• 浓度: 10 mg/mL (840012C-25mg); 25 mg/mL (840012C-100mg); 25 mg/mL (840012C-50mg)
• 脂质类型: phosphoglycerides
• 运输: dry ice
• 储存温度: −20°C
• SMILES字符串: [Na+].[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCC\C=C/C\C=C/CCCCC)OCC(O)CO[P](=O)([O-])OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCC\C=C/C\C=C/CCCCC
• InChI: 1S/C81H142O17P2.2Na/c1-5-9-13-17-21-25-29-33-37-41-45-49-53-57-61-65-78(83)91-71-76(97-80(85)67-63-59-55-51-47-43-39-35-31-27-23-19-15-11-7-3)73-95-99(87,88)93-69-75(82)70-94-100(89,90)96-74-77(98-81(86)68-64-60-56-52-48-44-40-36-32-28-24-20-16-12-8-4)72-92-79(84)66-62-58-54-50-46-42-38-34-30-26-22-18-14-10-6-2;;/h21-28,33-40,75-77,82H,5-20,29-32,41-74H2,1-4H3,(H,87,88)(H,89,90);;/q;2*+1/p-2/b25-21-,26-22-,27-23-,28-24-,37-33-,38-34-,39-35-,40-36-;;/t76-,77-;;/m1../s1
• InChI key: ZGSPNIOCEDOHGS-LBOJVHLDSA-L

说明

一般描述

Cardiolipin is a phospholipid found in the inner membrane of the mitochondria. It is synthesized from phosphatidylglycerol and cytidinediphosphate-diacylglycerol.[1] It consists of two phosphatidyl residues, which are linked by a glycerol group.[2]

应用

Heart CA has been used in the Mycobacterium lipid extraction and in β- Hexosaminidase release and calcium mobilization assays.[3] It maybe used for liposome synthesis[4]. It may also be used as a lipid standard for the in situ analysis and characterization of cardiolipins.[5]

生化/生理作用

Cardiolipin is involved in maintaining the structure and function of the mitochondria. It also serves as a co-factor for stimulating mitochondrial enzymes and mediates mitochondrial apoptosis. Cardiolipin is associated with the oxidative phosphorylation system for the adenine triphosphate (ATP) synthesis in the inner membrane of the mitochondria.[1] Deficiency of cardiolipin is associated with variation of mitochondrial membrane structure and function. It is also associated with Barth syndrome.[2][1]

包装

5 mL Clear Glass Sealed Ampule (840012C-100mg)

5 mL Clear Glass Sealed Ampule (840012C-25mg)

5 mL Clear Glass Sealed Ampule (840012C-50mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 象形图: GHS06,GHS08
• 警示用语：: Danger
• 危险声明: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• 预防措施声明: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• 危险分类: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• 靶器官: Central nervous system, Liver,Kidney
• 储存分类代码: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• 闪点(°F): does not flash
• 闪点(°C): does not flash