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810172P

Avanti

14:0-12:0 NBD PA

Avanti Research™ - A Croda Brand 810172P, powder

别名:

1-myristoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphate (ammonium salt)

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1 MG
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1 MG
$381.00

About This Item

经验公式（希尔记法）:
C35H62N5O11P
CAS号:
474942-93-3
分子量:
759.87
MDL编号:
MFCD00870345
UNSPSC代码:
12352211
NACRES:
NA.25

$381.00

请联系客服了解存货情况
获取大包装报价

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 1 mg (810172P-1mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 810172P

运输

dry ice

储存温度

−20°C

相关类别

一般描述

Phosphatidic acid (PA) is an anionic phospholipid with a phosphomonoester polar head group and two long hydrophobic acyl chains.[1] It constitutes 1-4% of membrane lipids.[1] NBD PA possess fluorescence analog, 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at sn-2 fatty acid of PA.[2]

生化/生理作用

Phosphatidic acid (PA) serves as a parent compound to generate other phospholipids.[3] It is a major signaling molecule in the regulation of cellular processes including cell proliferation, secretion and reproduction, cytoskeletal organization, and many more.[1]

包装

5 mL Amber Glass Screw Cap Vial (810172P-1mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

历史批次信息供参考:

分析证书(COA)

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Mikhail A Zhukovsky et al.
FEBS letters, 593(17), 2428-2451 (2019-08-01)
Phosphatidic acid (PA) is the simplest cellular glycerophospholipid characterized by unique biophysical properties: a small headgroup; negative charge; and a phosphomonoester group. Upon interaction with lysine or arginine, PA charge increases from -1 to -2 and this change stabilizes protein-lipid
Phosphatidic acid in membrane rearrangements
Zhukovsky MA, et al.
Febs Letters, 593(17), 2428-2451 (2019)
Interaction of amyloid beta-protein with anionic phospholipids: possible involvement of Lys28 and C-terminus aliphatic amino acids
Chauhan A, et al.
Neurochemical Research, 25(3), 423-429 (2000)
A Chauhan et al.
Neurochemical research, 25(3), 423-429 (2000-04-13)
Fibrillar amyloid beta-protein (Abeta) is the major protein of amyloid plaques in the brains of patients with Alzheimer's disease (AD). The mechanism by which normally produced soluble Abeta gets fibrillized in AD is not clear. We studied the effect of
Karen M Henkels et al.
Oncotarget, 7(30), 47002-47017 (2016-06-04)
The intracellular concentration of the mitogen phosphatidic acid (PA) must be maintained at low levels until the need arises for cell proliferation. How temporal and spatial trafficking of PA affects its target proteins in the different cellular compartments is not

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