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790404P

Avanti

18:1 DGS-NTA(Ni)

Avanti Research™ - A Croda Brand

别名:

1,2-二-（9Z-十八烯酰基）-sn-甘油-3-[（N-（5-氨基-1-羧基戊基）亚氨基二乙酸）琥珀酰基]（镍盐）；狗NTA

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5 MG
$221.00
10 MG
$430.00
25 MG
$609.00

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5 MG
$221.00
10 MG
$430.00
25 MG
$609.00

About This Item

经验公式（希尔记法）:
C53H93N2O15Ni
CAS号:
231615-77-3
分子量:
1057.00
MDL號碼:
MFCD00056438
分類程式碼代碼:
12352211
NACRES:
NA.25

$221.00

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描述

1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt)

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 10 mg (790404P-10mg)
pkg of 1 × 25 mg (790404P-25mg)
pkg of 1 × 5 mg (790404P-5mg)

製造商／商標名

Avanti Research™ - A Croda Brand

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

1,2-二油酰基-sn-甘油基-3-[（N-（5-氨基-1-羧基戊基）亚氨基二乙酸）琥珀酰基]氮川三乙酸（NTA）（18：1 DGS-NTA（Ni））是含镍的共轭磷脂[1] 。[2]NTA与镍离子中存在六个配位点中的四个螯合。[3]

應用

1,2-二油酰基-sn-甘油基-3-[（N-（5-氨基-1-羧基戊基）亚氨基二乙酸）琥珀酰基]（镍盐）（18：1 DGS-NTA（Ni））用于：
  • 制备含卟啉-磷脂（PoP）偶联物的脂质体，用于蛋白质和肽的结合研究[1]
  • 制备纳米级多层囊泡（NMV），用于抗原递送研究[2]
  • 作为小单层囊泡（SUV）成分，用于制备平面脂质膜（PM） [4]

生化／生理作用

1,2-二油酰基-sn-甘油基-3-[（N-（5-氨基-1-羧基戊基）亚氨基二乙酸）琥珀酰基]氮川三乙酸（NTA）（18：1 DGS-NTA（Ni））可用于结构生物学，尤其适合重组组氨酸标签结合蛋白。 [1] 虽然用处很大，但纳米颗粒在生物样品中存在稳定性问题。因此，NTA-脂质缀合物主要用作脂质体或纳米颗粒涂层。[1]基于DGS-NTA（Ni）的纳米级多层囊泡（NMV）是有效的疫苗递送系统。[2]

包裝

5 mL透明玻璃密封安瓿（790404P-25mg）

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

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