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Merck

700096P

Avanti

7α,24(S)-dihydroxycholesterol

Avanti Research - A Croda Brand

别名:

cholest-5-ene-3β,7α,24(S)-triol

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About This Item

经验公式(希尔记法):
C27H46O3
分子量:
418.65
分類程式碼代碼:
12352211
NACRES:
NA.25

描述

7α,24(S)-dihydroxycholesterol

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 1 mg (700096P-1mg)

製造商/商標名

Avanti Research - A Croda Brand

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

7α,24(S)-dihydroxycholesterol (24(S)-dihydroxycholesterol) is synthetically synthesized via from E-α, β-enone from the starting compounds Arsonium ylide and J-tert-butyldimethylsilyloxy-bisnor-5-cholenaldehyde. This undergoes further changes to form 7α,24(S)-dihydroxycholesterol.

生化/生理作用

7α,24(S)-dihydroxycholesterol (24(S)-dihydroxycholesterol) is a ligand for liver X receptor (LXR) and binds to the ligand binding domain of LXRα and LXRβ.

包裝

5 mL Amber Glass Screw Cap Vial (700096P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


分析证书(COA)

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Simple, stereocontrolled syntheses of 24 (S), 25-epoxy-22 (R)-hydroxycholesterol, 22 (R), 24 (S)-dihydroxycholesterol and diastereomers, new ligands for binding and activation of LXRs
Corey EJ and Grogan MJ
Tetrahedron Letters, 39(51), 9355-9356 (1998)

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