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描述
7α,24(S)-dihydroxycholesterol
化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 1 mg (700096P-1mg)
製造商/商標名
Avanti Research™ - A Croda Brand
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
7α,24(S)-dihydroxycholesterol (24(S)-dihydroxycholesterol) is synthetically synthesized via from E-α, β-enone from the starting compounds Arsonium ylide and J-tert-butyldimethylsilyloxy-bisnor-5-cholenaldehyde. This undergoes further changes to form 7α,24(S)-dihydroxycholesterol.
生化/生理作用
7α,24(S)-dihydroxycholesterol (24(S)-dihydroxycholesterol) is a ligand for liver X receptor (LXR) and binds to the ligand binding domain of LXRα and LXRβ.
包裝
5 mL Amber Glass Screw Cap Vial (700096P-1mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
Simple, stereocontrolled syntheses of 24 (S), 25-epoxy-22 (R)-hydroxycholesterol, 22 (R), 24 (S)-dihydroxycholesterol and diastereomers, new ligands for binding and activation of LXRs
Tetrahedron Letters, 39(51), 9355-9356 (1998)
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