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形狀
powder
用途
sufficient for ~275 reactions
製造商/商標名
Avanti Research™ - A Croda Brand
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
The CerS Assay Kit provides an easy to use assay for measuring CerS activity in biological samples. This Kit offers the advantage of a short assay time requiring only small amounts of biological material while eliminating TLC as a separation technique with its attendant degradation of NBD sphinganine.
生化/生理作用
Ceramide synthase (cerS) catalyzes the acylation of sphinganine (dihydrosphingosine) to yield dihydroceramide and sphingosine to yield ceramide. There are six cerS (cerS1-6), which differ in their specificity to yield ceramides of different chain length. Ceramide is a key intermediate in sphingolipid metabolism and an key signaling molecule.
包裝
Kit contains:
0.3mg 16:0 fatty acyl-CoA
0.1mg NBD Sphinganine
0.3mg 16:0 fatty acyl-CoA
0.1mg NBD Sphinganine
儲存和穩定性
Note: this product should be stored at -20° for up to 6 months.
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
10 - Combustible liquids
The equilibrium between long and very long chain ceramides is important for the fate of the cell and can be influenced by co-expression of CerS.
The International Journal of Biochemistry & Cell Biology, 45(7), 1195-1203 (2013)
Mammalian Ceramide Synthases
IUBMB Life, 62(5), 347?356-347?356 (2010)
When do Lasses (longevity assurance genes) become CerS (ceramide synthases)? Insights into the regulation of ceramide synthesis.
The Journal of Biological Chemistry, 281(35), 25001-25005 (2006)
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