W332208

硫胺 盐酸盐

≥98%, FCC, FG

• 别名: 硫胺素 盐酸盐, 维生素 B ₁ 盐酸盐
• 经验公式（希尔记法）: C₁₂H₁₇ClN₄OS · HCl
• CAS号: 67-03-8
• 分子量: 337.27
• FEMA编号: 3322
• Beilstein: 3851771
• EC 号: 200-641-8
• 欧洲委员会编号: 4226
• MDL编号: MFCD00012780
• UNSPSC代码: 12164502
• PubChem化学物质编号: 24901639
• Flavis编号: 16.027
• NACRES: NA.21

属性

• 生物来源: synthetic
• 质量水平: 400
• 等级: FG; Halal; Kosher
• Agency: meets purity specifications of JECFA
• 管理合规性: EU Regulation 1334/2008 & 872/2012; FCC
• 方案: ≥98%
• 表单: powder or crystals
• 颜色: white to yellow-white
• mp: 250 °C (dec.) (lit.)
• 溶解性: H₂O: 1 g/10 mL, clear, colorless
• 应用: flavors and fragrances
• 文件: see Safety & Documentation for available documents
• 食品过敏原: no known allergens
• 性状检查: sour
• SMILES字符串: CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]
• InChI: 1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
• InChI key: DPJRMOMPQZCRJU-UHFFFAOYSA-M

说明

一般描述

Thiamine hydrochloride is a water-soluble vitamin generally used as a nutrient supplement.[1] When it undergoes heat-degradation, it may form volatile flavor compounds such as hydrogen sulfide, 2-methylthiopehene, 2-methylfuran, and 4,5-dihydro-2-methylthiophene.[2]

应用

• Construction of hyaluronic acid-functionalized magnolol nanoparticles for ulcerative colitis treatment.: This innovative study explores the synthesis of nanoparticle systems using hyaluronic acid-functionalized magnolol, highlighting thiamine hydrochloride′s role in enhancing therapeutic efficacy and stability in gastrointestinal treatments. This research underlines the biochemical application of thiamine hydrochloride in developing advanced drug delivery systems (Li Y et al., 2024).


• Constructing Highly Stable Zinc Metal Anodes via Induced Zn(002) Growth.: Investigates the electrochemical stability of zinc anodes, with thiamine hydrochloride playing a critical role in modulating the electrochemical properties and enhancing the anode′s performance, showcasing its potential in next-generation battery technologies (Hu S et al., 2024).


• Subclinical thiamine deficiency results in failed reproduction in Arctic foxes.: This study identifies the pivotal role of thiamine hydrochloride in preventing reproductive failures linked to nutritional deficiencies in wildlife, extending its application beyond human health to include environmental and conservation aspects (Jackson C et al., 2024).


• Density Functional Theory and Density Functional Tight Binding Studies of Thiamine Hydrochloride Hydrates.: Highlights computational studies on the molecular structure and stability of thiamine hydrochloride, providing crucial insights into its physicochemical properties and interactions at the molecular level, critical for pharmaceutical formulations (Napiórkowska E et al., 2023).


• Effects of Nutrients on the Growth of and Free Exopolysaccharide Biosynthesis by Streptococcus thermophilus 937 in a Chemically Defined Medium.: Examines the influence of thiamine hydrochloride among other nutrients on the microbial synthesis processes, underlining its essential role in microbial nutrition and metabolic engineering (Wa Y et al., 2023).

安全信息

• 象形图: GHS07
• 警示用语：: Warning
• 危险声明: H319
• 预防措施声明: P264 - P280 - P305 + P351 + P338 - P337 + P313
• 危险分类: Eye Irrit. 2
• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable
• 个人防护装备: Eyeshields, Gloves, type N95 (US)