QBD10512

Azido-dPEG^®₈-acid

• 别名: Polyethylene glycol
• 经验公式（希尔记法）: C₁₉H₃₇N₃O₁₀
• CAS号: 1214319-92-2
• 分子量: 467.51
• MDL编号: MFCD21363300
• UNSPSC代码: 12352106
• PubChem化学物质编号: 329823934
• NACRES: NA.22

属性

• 方案: >90%
• 表单: solid or viscous liquid
• 反应适用性: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• 官能团: azide; carboxylic acid
• 聚合物结构设计: shape: linear; functionality: heterobifunctional
• 运输: ambient
• 储存温度: −20°C
• SMILES字符串: OC(CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O
• InChI: 1S/C19H37N3O10/c20-22-21-2-4-26-6-8-28-10-12-30-14-16-32-18-17-31-15-13-29-11-9-27-7-5-25-3-1-19(23)24/h1-18H2,(H,23,24)
• InChI key: URUGOEBULOZLBF-UHFFFAOYSA-N

说明

特点和优势

The azido-dPEG^®₈ contains an azide function on one end of a single molecular weight dPEG^® spacer (32.2Å) and a reactive group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

法律信息

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable