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Merck

M9775

Sigma-Aldrich

4-(N-马来酰亚胺)二苯甲酮

别名:

二苯甲酮-4-马来酰亚胺

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About This Item

经验公式(希尔记法):
C17H11NO3
CAS号:
分子量:
277.27
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

反應適用性

reagent type: cross-linking reagent

溶解度

chloroform: 50 mg/mL
DMF: soluble

儲存溫度

2-8°C

SMILES 字串

O=C1C=CC(=O)N1c2ccc(cc2)C(=O)c3ccccc3

InChI

1S/C17H11NO3/c19-15-10-11-16(20)18(15)14-8-6-13(7-9-14)17(21)12-4-2-1-3-5-12/h1-11H

InChI 密鑰

OZIZEXQRIOURIJ-UHFFFAOYSA-N

應用

含巯基特异性基团和光敏基团的双异官能化交联剂。通常,初始反应在 pH 为 6.8 (6.5-7.0) 时通过硫醚偶联至含游离巯基的分子。紫外光 (250nm) 照射的过程中通过双自由基激发态发生二次键合。二苯甲酮对 C-H 插入表现出更大的特异性并且在水中比类似试剂更稳定。一般说来,它们附接更有效,因为可对其反复照射;然而可能需要更强的照射。与类似试剂相比,二苯甲酮对还原反应不敏感。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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L Sahlman et al.
The Journal of biological chemistry, 272(47), 29518-29526 (1997-12-31)
Bacterial detoxification of mercuric ion depends on the presence of one or more integral membrane proteins (MerT and/or MerC) whose postulated function is in transport of Hg2+ from a periplasmic Hg2+-binding protein (MerP) to cytoplasmic mercuric reductase. In this study
Mayumi Tamura et al.
Biological & pharmaceutical bulletin, 34(6), 929-932 (2011-06-02)
LEC-1 is the first tandem repeat-type galectin isolated from an animal system; this galectin has two carbohydrate recognition domains in a single polypeptide chain. Because its two lectin domains have different sugar-binding profiles, these domains are thought to interact with
Y Luo et al.
Journal of molecular biology, 296(3), 899-910 (2000-03-15)
The interaction sites of rabbit skeletal troponin I (TnI) with troponin C (TnC), troponin T (TnT), tropomyosin (Tm) and actin were mapped systematically using nine single cysteine residue TnI mutants with mutation sites at positions 6, 48, 64, 89, 104
S Basu et al.
The Biochemical journal, 296 ( Pt 3), 577-583 (1993-12-15)
Treatment of murine leukaemia virus reverse transcriptase with benzophenone 4-maleimide inactivates DNA polymerase activity, but has no effect on the RNAase H function. Kinetic measurements indicated that benzophenone 4-maleimide is a competitive inhibitor with respect to template-primer binding, but is
Yoichiro Arata et al.
Biochemistry, 41(37), 11301-11307 (2002-09-11)
Using a combination of cysteine mutagenesis and covalent cross-linking, we have identified subunits in close proximity to specific sites within subunit B of the vacuolar (H(+))-ATPase (V-ATPase) of yeast. Unique cysteine residues were introduced into subunit B by site-directed mutagenesis

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