L040031

Cap A

• UNSPSC代码: 12352200

属性

• 类型: for DNA synthesis
• 质量水平: 200
• 产品线: Proligo Reagents
• 浓度: 97.0-119.0 g/L (acetic anhydride, titration)
• 颜色: clear colorlessto brownish

说明

一般描述

Cap A solution consists of acetic anhydrideanhydride, lutidine, and tetrahydrofuran (THF).

应用

Cap A solution is used after the phosphoramidite reaction/coupling step.

生化/生理作用

Cap A solution aborts chains bearing unreacted 5′ hydroxyl groups due to failure of reaction with activated phosphoramidite (typically, 1 to 2% of growing oligonucleotide chains in each synthesis cycle). These unreacted 5′ hydroxyl groups are capped with an acetyl group and thus rendered unreactive for subsequent synthesis steps.

安全信息

• 象形图: GHS02,GHS06,GHS08,GHS05
• 警示用语：: Danger
• 危险声明: H225,H302,H315,H318,H331,H335,H336,H351
• 预防措施声明: P210 - P280 - P301 + P312 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• 危险分类: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• 靶器官: Respiratory system
• 补充剂危害: EUH019
• 储存分类代码: 3 - Flammable liquids
• WGK: WGK 3