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方案
97%
表单
powder
mp
185-187 °C (lit.)
SMILES字符串
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)C(=CC[C@@]24[H])C(C)=O
InChI
1S/C21H28O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h6,12,16,18-19H,4-5,7-11H2,1-3H3/t16-,18-,19-,20-,21+/m0/s1
InChI key
VRRHHTISESGZFN-RKFFNLMFSA-N
基因信息
human ... CYP17A1(1586)
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警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
T L Glass et al.
Journal of steroid biochemistry, 21(1), 65-72 (1984-07-01)
Eubacterium sp. 144 biotransformed 16-dehydroprogesterone by initially hydrating approx 50% to 16 alpha-hydroxyprogesterone. The detection of this reaction was dependent, in part, on the solubility state of 16-dehydroprogesterone and was less extensive when the concentration of methanol was insufficient to
T L Glass et al.
Applied and environmental microbiology, 49(5), 1146-1153 (1985-05-01)
Suspensions of Eubacterium sp. strain 144, prepared from cells grown with 16-dehydroprogesterone, catalyzed the reduction of this steroid to 17-isoprogesterone at a very low rate. Modifications of the assay to optimize the pH (5.5) and increase the steroid solubility (10%
Comparison of the cardiotonic response of ouabain, androstan-3-one, 16-dehydroprogesterone, and conjugated estrogens.
A Woods et al.
Proceedings of the Western Pharmacology Society, 34, 113-115 (1991-01-01)
A E Schindler et al.
Biology of the neonate, 27(3-4), 192-207 (1975-01-01)
Four different methods of isolation and purification were utilized to study steroids in urine of male newborns which was collected during the first 5 days of life. These methods included celite column, ion exchange column and thin-layer chromatography, solvolysis and
Ismael Samudio et al.
Molecular cancer therapeutics, 4(12), 1982-1992 (2005-12-24)
In this study, the antileukemic effects of three isomeric pregnadienedione steroids [i.e., cis-guggulsterone, trans-guggulsterone, and 16-dehydroprogesterone] were investigated in HL60 and U937 cells as well as in primary leukemic blasts in culture. Our results show that all three compounds inhibited
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