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Merck

ALD00596

Sigma-Aldrich

N-((1S,2S)-1-(3,5-Di-tert-butylphenyl)-2-(quinolin-2-yl)butyl)acetamide

≥95%

别名:

Chiral acetyl-protected aminoethyl quinoline ligand, Et-APAQ

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About This Item

经验公式(希尔记法):
C29H38N2O
分子量:
430.62
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.22

品質等級

化驗

≥95%

形狀

powder or crystals

反應適用性

reaction type: C-C Bond Formation
reagent type: catalyst
reagent type: ligand
reaction type: C-H Activation

應用

This chiral acetyl-protected aminoethyl quinoline (APAQ) ligand was developed by the Yu group for ligand-enabled acceleration of Pd-catalyzed enantioselective β-methylene C–H functionalization, which is important for the generation of β-chiral centers in asymmetric synthesis.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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相关内容

The Yu program centers around the discovery of catalytic carbon–carbon and carbon–heteroatom bond forming reactions based on C–H activation. Target transformations are selected to enable 1) the use of simple and abundant starting materials such as aliphatic acids, amines and alcohols, and 2) disconnections that drastically shorten the synthesis of a drug molecule or a major class of biologically active compounds.

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