跳转至内容
Merck

915823

Sigma-Aldrich

Fmoc-Cys(2,4-hexadiene)-OH

≥95%

别名:

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-((2E,4E)-hexa-2,4-dien-1-yl)-L-cysteine, Diene-containing cysteine for peptide macrocylization

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C24H25NO4S
分子量:
423.52
分類程式碼代碼:
12352209

化驗

≥95%

形狀

solid

mp

91-96 °C

儲存溫度

−20°C

應用

Fmoc-Cys(2,4-hexadiene)-OH is a diene-containing amino acid developed in the Moellering lab for the preparation of Diels-Alder-cyclized peptides for macrocyclization and peptide stabilization. Peptide macrocycles are of increasing interest for improving peptide bioactivity and properties as well as their potential to study, stabilize, or inhibit protein-protein interactions (PPIs).

相關產品

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Jeffrey E Montgomery et al.
Journal of the American Chemical Society, 141(41), 16374-16381 (2019-09-17)
Macrocyclization can improve bioactive peptide ligands through preorganization of molecular topology, leading to improvement of pharmacologic properties like binding affinity, cell permeability, and metabolic stability. Here we demonstrate that Diels-Alder [4 + 2] cycloadditions can be harnessed for peptide macrocyclization

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门