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Merck

900760

Sigma-Aldrich

Sodium 5-(trifluoromethyl)pyridine-2-sulfinate

≥95%

别名:

Willis 5-trifluoromethyl pyridine 2-sulfinate

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About This Item

经验公式(希尔记法):
C6H3F3NNaO2S
分子量:
233.14
分類程式碼代碼:
12352200
NACRES:
NA.22

化驗

≥95%

形狀

powder

反應適用性

reaction type: C-C Bond Formation

mp

340 °C (dec)

應用

This 2-pyridylsulfinate enables Suzuki-Miyaura cross coupling with aryl halides to access diverse pyridine derivatives as reported by the laboratory of Michael Willis.. No longer impeded by unstable 2-pyridyl boronates, the sulfinate alternatives provide Pd-catalyzed coupling routes to therapeutically valuable pyridine rings.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

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Description: Professor Willis and partners at Pfizer have shown with pyridine-2- sulfinates a palladium-catalyzed desulfinylative cross-coupling process can be realized.

相关内容

Description: Professor Willis and partners at Pfizer have shown with pyridine-2- sulfinates a palladium-catalyzed desulfinylative cross-coupling process can be realized.

Research in the Willis group is focused on the development of new catalysts and reactions for synthetic chemistry. The group is particularly interested in addressing synthetic challenges that are applicable to the pharmaceutical and agrochemical industries.

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