跳转至内容
Merck
所有图片(2)

主要文件

查看所有文档

900744

Sigma-Aldrich

TMS-N-ethynyl-N,4-dimethylbenzenesulfonamide

≥95%

别名:

N,4-Dimethyl-N-((trimethylsilyl)ethynyl)benzenesulfonamide, TMS-N-methylynetoluenesulfonamide, TMS-MTYsA

登录查看公司和协议定价
所有图片(2)

About This Item

经验公式（希尔记法）:
C13H19NO2SSi
分子量:
281.45
分類程式碼代碼:
12352200

化驗

≥95%

形狀

solid

mp

55 °C

官能基

sulfonamide

儲存溫度

2-8°C

SMILES 字串

CC1=CC=C(S(=O)(N(C)C#C[Si](C)(C)C)=O)C=C1

應用

TMS-N-ethynyl-N,4-dimethylbenzenesulfonamide (TMS-MTYsA) is an air- and moisture-stable ynamide demonstrated to be an efficient and high-yielding coupling reagent for selective amide and peptide bond formation[1][2][3] under mild reaction conditions without racemization.[4] The product is supplied as the TMS-protected ynamide, which can be easily deprotected in situ without isolating the product.

其他說明

Ynamides as Racemization-Free Coupling Reagents for Amide and Peptide Synthesis

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助，请联系 客户支持

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Regio-and Stereoselective Synthesis of 2-Amino-1, 3-diene Derivatives by Ruthenium-Catalyzed Coupling of Ynamides and Ethylene.
Saito N, et al.
Organic Letters, 13(10), 2718-2721 (2011)
Gold-Catalyzed Intermolecular Nitrene Transfer from 2 H-Azirines to Ynamides: A Direct Approach to Polysubstituted Pyrroles.
Zhu L, et al.
Organic Letters, 17(1), 30-33 (2014)
Ynamides as Racemization-Free Coupling Reagents for Amide and Peptide Synthesis.
Hu L, et al.
Journal of the American Chemical Society, 138(40), 13135-13138 (2016)
Enantioselective synthesis of β-amino acid derivatives via nickel-promoted regioselective carboxylation of ynamides and rhodium-catalyzed asymmetric hydrogenation.
Saito N, et al.
Organic & Biomolecular Chemistry, 14(42), 10080-10089 (2016)

Questions

Reviews

No rating value

Active Filters

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门