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Merck

750026

Sigma-Aldrich

3α,5β-Tetrahydroaldosterone

≥98% (CP)

别名:

11β,18-Epoxy-3α,18,21-trihydroxy-5β-pregnan-20-one, 5β-Pregnan-11β,18-epoxy-3α,18,21-triol-20-one

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About This Item

经验公式(希尔记法):
C21H32O5
CAS号:
分子量:
364.48
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.24

品質等級

化驗

≥98% (CP)

形狀

powder

技術

mass spectrometry (MS): suitable

儲存溫度

−20°C

SMILES 字串

C[C@]12CC[C@@H](O)C[C@H]1CC[C@H]3[C@@H]4CC[C@H](C(=O)CO)[C@@]45C[C@H](O[C@@H]5O)[C@H]23

InChI

1S/C21H32O5/c1-20-7-6-12(23)8-11(20)2-3-13-14-4-5-15(16(24)10-22)21(14)9-17(18(13)20)26-19(21)25/h11-15,17-19,22-23,25H,2-10H2,1H3/t11-,12-,13+,14+,15-,17+,18-,19+,20+,21-/m1/s1

InChI 密鑰

JDEYOKPHRJVBQO-BMDKAXIVSA-N

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包裝

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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M Egfjord et al.
The American journal of physiology, 260(4 Pt 2), F536-F548 (1991-04-01)
The metabolism of aldosterone (Aldo) at 4 nM was studied by radioimmunoassay and by high-performance liquid chromatography in isolated perfused liver (IPL), isolated perfused kidney (IPK), and combined isolated perfused liver and kidney (CIPLK) of male Wistar rats. Effect of
T Miyazaki et al.
Endocrinologia japonica, 36(1), 95-100 (1989-02-01)
Analysis of urinary metabolites of [1, 2-3H]-3 alpha, 5 beta-tetrahydroaldosterone was performed in male guinea-pigs. Separation of urinary metabolites was carried out by means of DEAE-Sephadex A-25 column chromatography and four fractions (fraction A to fraction D) were detected. 46-50%
B G Wolthers et al.
Clinica chimica acta; international journal of clinical chemistry, 236(1), 33-43 (1995-04-30)
A case is described of a newborn, admitted to hospital because of severe salt loss at the age of 1 month. Subsequent analysis of urinary steroid excretion, by gas chromatography and gas chromatography-mass spectrometry, revealed that the patient suffered from
B J Koopman et al.
Journal of chromatography, 378(2), 283-292 (1986-06-13)
A newly devised procedure for a simultaneous determination of urinary tetrahydroaldosterone and aldosterone is described. The procedure is based on deconjugation and acetalization, followed by extraction and derivatization of the urinary compounds to their trimethylsilyl ethers and subsequent gas chromatographic-mass
S Ulick et al.
The Journal of clinical endocrinology and metabolism, 76(4), 873-878 (1993-04-01)
18-Hydroxycortisol and 18-oxocortisol have been isolated from the urine of patients with aldosterone producing adrenocortical adenomas, but not from those with idiopathic hyperaldosteronism associated with bilateral adrenal hyperplasia. These C-18 oxygenated cortisols are biosynthesized by the substitution of cortisol for

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