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质量水平
方案
97%
表单
solid
mp
75-79 °C (lit.)
官能团
anhydride
ester
fluoro
SMILES字符串
Fc1ccc2C(=O)OC(=O)c2c1
InChI
1S/C8H3FO3/c9-4-1-2-5-6(3-4)8(11)12-7(5)10/h1-3H
InChI key
XVMKZAAFVWXIII-UHFFFAOYSA-N
一般描述
4-Fluorophthalic anhydride is a fluorinated building block commonly used in chemical synthesis for the preparation of polyimide, pesticides, herbicides, and fungicides. It can be synthesized by treating 4-chlorophthalic anhydride with potassium fluoride.[1]
应用
4-Fluorophthalic anhydride can be used as a reactant to prepare:
- 4-amino substituted phthalimides applicable as potential fluorescent probes and fluorescent bioactive compounds.[2]
- 4,4′-bis(4-fluorophthalimido)diphenyl ether monomer, which is used in the synthesis of cardo polymers via nucleophilic substitution polymerization reaction.[3]
- Asymmetric polyimides by a solution polycondensation reaction.[4]
警示用语：
Danger
危险分类
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
其他客户在看
Synthesis of high performance phenolphthalein-based cardo poly (ether ketone imide) s via aromatic nucleophilic substitution polymerization
Liu Jiangtao, et al.
Polymer, 70, 30-37 (2015)
Synthesis of cardo containing asymmetric poly (ether-naphthalimide-phthalimide) s
Mushtaq N, et al.
Polymer International, 66(11), 1633-1639 (2017)
Vu H Nguyen et al.
EJNMMI research, 3(1), 80-80 (2013-12-18)
Sigma2 (σ2) receptors are highly expressed in cancer cell lines and in tumours. Two novel selective 18F-phthalimido σ2 ligands, 18F-SIG343 and 18F-SIG353, were prepared and characterised for their potential tumour imaging properties. Preparation of 18F-SIG343 and 18F-SIG353 was achieved via
Saturated vapor pressure of 4-fluorophthalic anhydride and 4-chlorophthalic anhydride and isobaric vapor-liquid phase equilibrium of 4-fluorophthalic anhydride+ 4-chlorophthalic anhydride: Measurement and modeling
LiRongRong, et al.
Fluid Phase Equilibria, 396, 35-42 (2015)
Efficient one-step synthesis of 4-amino substituted phthalimides and evaluation of their potential as fluorescent probes
Kindahl T and Chorell E
Organic & Biomolecular Chemistry, 12(25), 4461-4470 (2014)
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