638013

4-二苯基膦基苯甲酸 2-(三甲基硅基)乙酯 溶液

0.5 M in THF

• 经验公式（希尔记法）: C₂₄H₂₇O₂PSi
• CAS号: 566190-45-2
• 分子量: 406.53
• MDL编号: MFCD07369722
• UNSPSC代码: 12352108
• PubChem化学物质编号: 24882904

属性

• 反应适用性: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• 浓度: 0.5 M in THF
• 密度: 0.925 g/mL at 25 °C
• 官能团: phosphine
• SMILES字符串: C[Si](C)(C)CCOC(=O)c1ccc(cc1)P(c2ccccc2)c3ccccc3
• InChI: 1S/C24H27O2PSi/c1-28(2,3)19-18-26-24(25)20-14-16-23(17-15-20)27(21-10-6-4-7-11-21)22-12-8-5-9-13-22/h4-17H,18-19H2,1-3H3
• InChI key: QTYUNPJLGFKKRV-UHFFFAOYSA-N

说明

应用

4-Diphenylphosphanyl-benzoic acid 2-trimethylsilanyl-ethyl ester (DPPBE) was developed as an efficient alternative to triphenylphosphine in the Mitsunobu reaction since the phosphine oxide formed during the reaction can be easily removed during workup.[1]

Reagent for:

• Synthesis of alkenes
• Methylation of aldehydes
• Mitsunobu reactions

安全信息

• 象形图: GHS02,GHS08,GHS07
• 警示用语：: Danger
• 危险声明: H225,H319,H335,H351
• 预防措施声明: P210 - P280 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• 危险分类: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• 靶器官: Respiratory system
• 补充剂危害: EUH019
• 储存分类代码: 3 - Flammable liquids
• WGK: WGK 3
• 闪点(°F): -4.0 °F - closed cup
• 闪点(°C): -20 °C - closed cup