586579

5-氟吲哚-2-酮

97%

• 别名: 5-Fluoro-1,3-dihydroindol-2-one, 5-Fluoro-2,3-dihydro-2-oxoindole
• 经验公式（希尔记法）: C₈H₆FNO
• CAS号: 56341-41-4
• 分子量: 151.14
• MDL號碼: MFCD02179598
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24881126
• NACRES: NA.22

属性

• 化驗: 97%
• mp: 143-147 °C (lit.)
• SMILES 字串: Fc1ccc2NC(=O)Cc2c1
• InChI: 1S/C8H6FNO/c9-6-1-2-7-5(3-6)4-8(11)10-7/h1-3H,4H2,(H,10,11)
• InChI 密鑰: DDIIYGHHUMKDGI-UHFFFAOYSA-N

说明

應用

Reactant for preparation of:

• Glycogen synthase kinase 3 beta (GSK-3β) inhibitors
• Antitumor agents
• Cyclooxygenase 1/2 (COX-1/2) and 5-lipoxygenase (5-LOX) inhibitors
• Multitargeted Receptor Tyrosine Kinase Inhibitors
• Non-peptide thrombopoietin (TPO) receptor ligands
• Aurora kinase inhibitors
• Inhibitors of cyclin-dependent kinase CDK2/cyclin A
• Selective norepinephrine reuptake inhibitors
• B-cell lymphoma-extra large molecule (Bcl-XL) inhibitor Z36
• Inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1)

安全信息

• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)