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Merck

52730

Sigma-Aldrich

六甲基磷酰三胺

purum, ≥98.0% (GC)

别名:

HMPA, 三(二甲氨基)氧膦, 六甲基磷酸三胺

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About This Item

线性分子式:
[(CH3)2N]3PO
CAS号:
分子量:
179.20
Beilstein:
1099903
EC號碼:
MDL號碼:
分類程式碼代碼:
12352111
PubChem物質ID:
NACRES:
NA.22

蒸汽密度

6.18 (vs air)

蒸汽壓力

0.07 mmHg ( 25 °C)

等級

purum

化驗

≥98.0% (GC)

雜質

≤2.0% water (Karl Fischer)

折射率

n20/D 1.459 (lit.)
n20/D 1.459

bp

230-232 °C/740 mmHg (lit.)

mp

7 °C (lit.)

密度

1.03 g/mL at 25 °C (lit.)

SMILES 字串

CN(C)P(=O)(N(C)C)N(C)C

InChI

1S/C6H18N3OP/c1-7(2)11(10,8(3)4)9(5)6/h1-6H3

InChI 密鑰

GNOIPBMMFNIUFM-UHFFFAOYSA-N

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象形圖

Health hazardCorrosion

訊號詞

Danger

危險聲明

危險分類

Carc. 1B - Eye Dam. 1 - Muta. 1B - Skin Corr. 1C

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

291.2 °F - closed cup

閃點(°C)

144 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Robert B Grossman et al.
The Journal of organic chemistry, 68(3), 871-874 (2003-02-01)
Hexamethylphosphorous triamide (HMPT) and other phosphoramidites and phosphites have been found to be efficient catalysts for the Michael reaction of alkenones and alkynones with malonates, alpha-cyano esters, beta-keto esters, and nitro compounds. The relatively nontoxic, easily hydrolyzed HMPT catalyzes the
Knud Nairz et al.
Genome biology, 5(10), R83-R83 (2004-10-06)
We report the use of the cross-linking drug hexamethylphosphoramide (HMPA), which introduces small deletions, as a mutagen suitable for reverse genetics in the model organism Drosophila melanogaster. A compatible mutation-detection method based on resolution of PCR fragment-length polymorphisms on standard
Anthony J Pearson et al.
Organic letters, 6(13), 2121-2124 (2004-06-18)
[reaction: see text] Vicinal stereocontrol during nucleophilic addition of tert-butyl lithiopropionate to eta(6)-anisole chromium tricarbonyl complexes with differing para substituents has been studied. Excellent vicinal double stereoinduction (>99:1) was observed when the para substituent was Si(CH(3))(3), and this has been
Drug-HPMA-HuIg conjugates effective against human solid cancer.
Blanka Ríhová et al.
Advances in experimental medicine and biology, 519, 125-143 (2003-04-05)
Amanda C Jones et al.
Journal of the American Chemical Society, 130(19), 6060-6061 (2008-04-19)
Low-temperature rapid-injection NMR (RINMR) experiments were performed on tris(trimethylsilyl)methyllithium. In THF/Me2O solutions, the separated ion (1S) reacted faster than can be measured at -130 degrees C with MeI and substituted benzaldehydes (k >/= 2 s -1), whereas the contact ion

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