460516

(R)-(+)-4-氯-3-羟基丁酸乙酯

96%

• 线性分子式: ClCH₂CH(OH)CH₂CO₂C₂H₅
• CAS号: 90866-33-4
• 分子量: 166.60
• MDL编号: MFCD00211242
• UNSPSC代码: 12352101
• PubChem化学物质编号: 24869705
• NACRES: NA.22

属性

• 质量水平: 100
• 方案: 96%
• 旋光性: [α]23/D +14°, neat
• 光学纯度: ee: 97% (GLC)
• 折射率: n20/D 1.453 (lit.)
• 沸点: 93-95 °C/5 mmHg (lit.)
• 密度: 1.19 g/mL at 25 °C (lit.)
• 官能团: chloro; ester; hydroxyl
• SMILES字符串: CCOC(=O)C[C@@H](O)CCl
• InChI: 1S/C6H11ClO3/c1-2-10-6(9)3-5(8)4-7/h5,8H,2-4H2,1H3/t5-/m1/s1
• InChI key: ZAJNMXDBJKCCAT-RXMQYKEDSA-N

说明

应用

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate is a chiral building block that can be used:

• To prepare allyl stannane, a precursor for the total synthesis of macrolide iriomoteolide-1b.[1]
• As a starting material for the synthesis of a chiral g-αmino acid fragment, which in turn is used to prepare the immunosuppressive agent FR252921.[2]

安全信息

• 象形图: GHS05
• 警示用语：: Danger
• 危险声明: H318
• 预防措施声明: P280 - P305 + P351 + P338
• 危险分类: Eye Dam. 1
• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 3
• 闪点(°F): 235.4 °F - closed cup
• 闪点(°C): 113 °C - closed cup
• 个人防护装备: Eyeshields, Gloves, type ABEK (EN14387) respirator filter